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Galit Frydman Discusses JTH Research on Cerebral Vein Thrombosis Risk from Hormonal Contraceptives
Galit Frydman/LinkedIn
Sep 28, 2025, 10:06

Galit Frydman Discusses JTH Research on Cerebral Vein Thrombosis Risk from Hormonal Contraceptives

Galit Frydman, Founder and Chief Scientific Officer of Coagulo Medical Technologies, Inc., reposted from Journal of Thrombosis and Haemostasis (JTH) on LinkedIn:

“Yet another example of how femtech needs more attention. Hormonal birth control is such a popular form of birth control, yet it can pose life-threatening adverse events to the woman using it.

I never realized how much women’s, maternal and fetal medicine was behind until I had my own pregnancy and child.

The market size is not a question here….why is funding and why are companies so far behind on these issues? (lots of reasons for this! but I thought it would start an interesting conversation on this platform)”

Journal of Thrombosis and Haemostasis (JTH) has shared a post on LinkedIn:

“The risk of cerebral vein thrombosis associated with different types of combined hormonal contraceptives: a case-control study

In this case-control study of 206 women with CVT and 868 controls, combined hormonal contraceptive (CHC) use was associated with a 10-fold higher risk of CVT. Risk increased with higher estrogen doses and was particularly elevated with fourth-generation pills (OR 28.3). Progestin-only and variable-dose CHCs carried a 6-fold increased risk. Importantly, thrombophilia and positive family history had synergistic effects, with odds ratios exceeding 200 in some subgroups.”

Title: The risk of cerebral vein thrombosis associated with different types of combined hormonal contraceptives: a case-control study

Authors: Maria Abbattista, Addolorata Truma, Ida Martinelli, Francesca Gianniello, Serena M. Passamonti, Marco Capecchi,  Andrea Artoni, Flora Peyvandi, Paolo Bucciarelli

Thrombosis

Read the full article here.

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Addolorata Truma Andrea Artoni cerebral vein thrombosis combined hormonal contraceptive (CHC) Flora Peyvandi Francesca Gianniello Galit Frydman Health Hematology Hemostasis Hemostasis Today Hormonal birth control Ida Martinelli Marco Capecchi Maria Abbattista Medicine Paolo Bucciarelli Serena M. Passamonti Thrombophilia thrombosis
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