Saul del Angel Pacheco Morales Gives Historical Review on Erythropoietin
Saul del Angel Pacheco Morales, Medical Advisor Oncology And High Specialty at Synthon México, shared on LinkedIn:
”ERYTHROPOIETIN
Erythropoietin (EPO): the treatment that changed anemia in kidney disease
For many years, people with chronic kidney disease suffered from severe anemia, extreme fatigue, and dependence on blood transfusions.
Today, this is very different, thanks to erythropoietin (EPO).
This image shows how this treatment came about:
1906 – Doctors discover that the body produces a substance that stimulates the formation of red blood cells. They exposed the serum of anemic animals to other animals and noticed an increase in red cell production.
1953–1957 – It is confirmed that the kidney is the organ that produces this substance (EPO).
1977 – Human erythropoietin is isolated for the first time.
1985 – Scientists learn how to produce EPO in the laboratory (recombinant erythropoietin).
1986–1987 – The first dialysis patients show increased hemoglobin levels and fewer transfusions.
1989 – The FDA approves EPO for treating anemia in kidney disease.
Thanks to EPO, millions of patients have been able to:
- Reduce or avoid transfusions
- Improve their quality of life
This is one of the great success stories of modern medicine and nephrology.”
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