David Murdock: Identifying High-Risk Variants of Uncertain Significance in Aortopathy Genes
David Murdock, Assistant Professor at The University of Texas Health Science Center at Houston, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Genetics in Medicine, adding:
“Excited to share our recent publication in Genetics in Medicine on identifying high-risk variants of uncertain significance (VUS) in aortopathy genes.
Using bioinformatic tools, we show how select VUS are strongly associated with increased risk of aortic dissection, helping move genetic findings closer to clinical action.”
Title: Using bioinformatic tools to identify high-risk variants of uncertain significance in aortopathy genes that increase aortic dissection risk
Authors: John DePaolo, Dong-chuan Guo, David R. Murdock, Alana C. Cecchi, Scott A. LeMaire, Hu Ying Shen, Anthony L. Estrera, Hazim J. Safi, Joseph S. Coselli, Josh Smith, Michael J. Bamshad, Scott Damrauer, Dianna M. Milewicz
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 31, 2026, 15:44Andrea Boccatonda: Special Issue on Pulmonary Embolism and Venous Thromboembolism
-
Aug 31, 2026, 15:41Adrien Jossart: Acute Thrombotic Storm Following Single Heparin Bolus
-
Aug 31, 2026, 15:36Bernhard Gerber: Myocardial Platelet Activation Linked to Microvascular Obstruction After STEMI
-
Aug 31, 2026, 15:34Higher Fibrinogen γ′ Linked to Increased Risk of Recurrent Arterial Thrombosis – Journal of Thrombosis and Haemostasis
-
Aug 31, 2026, 15:21Ney Carter Borges: Anticoagulation Versus Antiplatelet Therapy After TAVI ESC 26
-
Aug 31, 2026, 15:13Nahid A. Qushmaq: MicroRNAs as Prognostic Biomarkers in Septic Patients
-
Aug 31, 2026, 14:32Mahir Khalil Ibrahim Jallo: Hot Topic From The ESC 2026 Munich
-
Aug 31, 2026, 14:28Ruben Mesa: FDA Approves Ropeginterferon Alfa-2b for Essential Thrombocythemia
-
Aug 31, 2026, 14:28Francisco Chacón-Lozsán: Should We Anticoagulate AF Patients With Only One Non-Sex Stroke Risk Factor?