Bernhard Gerber: Myocardial Platelet Activation Linked to Microvascular Obstruction After STEMI
Bernhard Gerber, Editor in Chief European Heart Journal Cardiovascular Imaging at European Society of Cardiology, shared a post on LinkedIn about a recent article by Craig Balmforth et al., published in European Heart Journal, adding:
“EHJCVI Simultaneous publication presented at ESC congress 2026 in Munich
A fascinating study using 18F GP1 PET and CMR to investigate myocardial platelet activation and thrombosis in patients with microvascular obstruction (MVO) following STEMI.
MVO after STEMI was universally associated with myocardial platelet activation, extending beyond the structural abnormalities identified by cardiac MR.
These findings support an important mechanistic role of platelet mediated microvascular thrombosis in the development of no reflow and MVO, highlighting a potentially targetable biological pathway in a condition where effective therapies remain limited.
An exciting step toward better understanding the mechanisms underlying MVO and potentially identifying new therapeutic strategies for patients after STEMI.”
Title: Platelet activation and thrombosis in microvascular obstruction
Authors: Craig Balmforth , Alessandro Giaj Levra, Beth Whittington, Aidan Morgan, Mark G Macaskill, Evangelos Tzolos, Alex J Jordan, Tariq Ramtoola, Tim Clark, Michelle Rooney, Christophe Lucatelli, Edwin J R van Beek, Piotr J Slomka, Stephanie L Sellers, Norman Koglin, Andrew W Stephens, Iris Hardewig, David E Newby, Michelle C Williams, Marc R Dweck
Stay updated on all scientific advances with Hemostasis Today.
-
Aug 31, 2026, 17:06Nikolaos Ktenopoulos: COMPASS-ARTeCAT Trial Highlights Arterial Thrombosis in Patients With Cancer
-
Aug 31, 2026, 17:01Mark Kaplan: Same LDL-C, Different Coagulation, Different Outcomes, in FH
-
Aug 31, 2026, 16:55Kemal Karaagac: Milvexian Did Not Reduce Ischemic Events but Did Not Increase Fatal Bleeding
-
Aug 31, 2026, 16:47Improving Outcomes in AF-Related Stroke Beyond Anticoagulation at ESC 2026 – ESO
-
Aug 31, 2026, 16:39Shariq Shamim: Are We Going to Start DOAC post TAVI not DAPT?
-
Aug 31, 2026, 16:30Bartosz Hudzik: 5th Universal MI Definition Moves Closer to Biology in Women
-
Aug 31, 2026, 16:13Seema Dawood: Nucleated Red Blood Cells – What They Tell Us on a Peripheral Smear
-
Aug 31, 2026, 16:02Antonio Sorropago: Major Updates in Structural Heart Interventions
-
Aug 31, 2026, 15:44Andrea Boccatonda: Special Issue on Pulmonary Embolism and Venous Thromboembolism