Caitlin Raymond/LinkedIn
Jan 13, 2026, 16:38
Caitlin Raymond: Understanding TAMOF as a TTP-Like Process
Caitlin Raymond, Assistant Professor of Pathology and Transfusion Medicine at the University of Wisconsin-Madison, shared on LinkedIn:
”New post, inspired by a case I saw on service: TTP’s Little-Known Cousin: Understanding TAMOF as a TTP-Like Process.
TAMOF is often mislabeled as DIC or dismissed as “just sepsis.”
But mechanistically, it behaves like a secondary thrombotic microangiopathy — driven by endothelial activation, ultra-large vWF, and insufficient ADAMTS13 in context.
The labs are subtle:
- Low platelets
- High LDH
- ± MAHA
- Relatively preserved coagulation studies
Seeing the pattern matters, because TAMOF may be treatable, including consideration of plasma exchange.”
Read the full post here.
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