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Intra-Arterial Tenecteplase Improves Outcomes After Stroke Thrombectomy: Insights from the ANGEL-TNK Tria
Aug 22, 2025, 14:44

Intra-Arterial Tenecteplase Improves Outcomes After Stroke Thrombectomy: Insights from the ANGEL-TNK Tria

JAMA shared an insightful post on X:

“In patients with acute large vessel occlusion, intra-arterial tenecteplase after successful thrombectomy improved 90-day neurological outcomes without increasing hemorrhage or mortality.”

Title: Intra-arterial Tenecteplase for Acute Stroke After Successful Endovascular Therapy
The ANGEL-TNK Randomized Clinical Trial

Authors: Zhongrong Miao, Gang Luo, Ligang Song, Dapeng Sun, Wenhuo Chen, Xiaoxi Yao, Yuesong Pan, Yaou Liu, Guangxiong Yuan, Changming Wen, Ming Wei, Xueli Cai, Qingcheng Yang, Zhiming Zhou, Mingze Chang, Guangxian Nan, Jing Wang, Guangyu Xiang, Li Zhou, Wen Gao, Hong Zhang, Jiheng Hao, Chenghua Xu, Yaxuan Sun, Tingyu Yi, Ganghua Feng, Hongxing Han, Feng Gao, Ning Ma, Dapeng Mo, Xuan Sun, Yiming Deng, Xu Tong, Xiaoqing Li, Baixue Jia, Bo Wang, Zijun He, Ming Yang, Xingquan Zhao, Xuelei Zhang, Longhui Zhang, Shuo Li, Xin Tong, Jing Jing, Yunyun Xiong, Tao Liu, Zixiao Li, Zeguang Ren, Yilong Wang, David S. Liebeskind, Tudor G. Jovin, Thanh N. Nguyen, Yongjun Wang, Liping Liu, Bernard Yan, Xiaochuan Huo

Tenecteplase

Read the full article here.

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