M Velia Antonini/X
Oct 24, 2025, 10:16
Marta Velia Antonini: Myth-Busting on Perioperative Autologous Red Blood Cell Salvage
Marta Velia Antonini, Hematologist, Perfusionist ECMO and NRP Specialist and Chair of the Normothermic Regional Perfusion EuroELSO Working Group, shared on X:
“Myth-busting on perioperative autologous red blood cell salvage. Overview of the cell salvage process
- myth: cell-salvaged blood is of poor quality/inferior to allogeneic RBCs: if properly collected/processed, quality of cell salvaged RBCs exceeds allogeneic blood; here some considerations on morphology, oxygen unloading, lifespan, hemolysis, immunological effects
- myth: cell-salvaged blood increases bleeding: residual heparin typically have limited impact… but large-volume acute blood loss still requires factors replacement!
- myth: cell-salvaged blood is not safe in many surgeries: oncologic, obstetric, contaminated surgeries are NOT absolute contraindications… balance/mitigated risks!
- myth: cell-salvaged blood is not cost-effective: generally it is, particularly if employed selectively for high-risk cases
Title: Exploring Myths of Perioperative Autologous Red Blood Cell Salvage
Authors: Kaufman Margit, Jahr Jonathan, Klompas Allan, Perelman Seth, Raphael Jacob, Tan Gee Mei, Frank Steven, Waters Jonathan, Warner Matthew

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