AI generated
Aug 30, 2026, 12:51
When to Escalate Treatment in Sickle Cell Crisis – ISBT
International Society of Blood Transfusion (ISBT) shared a post on LinkedIn:
“Sickle Cell Crisis: When to Escalate Therapy – Part 2
In part 1, we looked at the clinical red flags that can signal a complicated or organ-threatening sickling crisis. In part 2, we explore when red cell exchange (RCE) should be considered and where PLEX may fit in severe, refractory disease.
Key messages:
- Know when urgent RCE may be indicated.
- Reduce HbS while avoiding hyperviscosity.
- PLEX is not routine first-line therapy.
- Escalate early and involve a multidisciplinary team when severe organ dysfunction persists.
The goal: interrupt sickling, reverse organ injury and prevent irreversible damage.
Stay connected with the ISBT Clinical Transfusion Working Party for more educational content and updates in clinical transfusion.”
See more in the gallery.
Stay updated with Hemostasis Today.
-
Oct 16, 2026, 17:22Wolfgang MiesbachÖ‰ What a Near-Perfect FISH Score Fails to See
-
Oct 16, 2026, 17:06Troels Wienecke: Connecting Myeloproliferative Disease and Ischemic Stroke
-
Oct 16, 2026, 17:03Only 5 Days Left to Submit Your Research for EAHAD 2027
-
Oct 16, 2026, 16:48Abdul Rahman: Reticulocyte Count and Bone Marrow Activity
-
Oct 16, 2026, 16:44DOAC Adherence in Stroke Patients With Atrial Fibrillation – International Journal of Stroke
-
Oct 16, 2026, 16:22Shannon Farmer: Driving Patient Blood Management Forward in Australia and New Zealand
-
Oct 16, 2026, 16:01Obi Light Ogbonnia: The Greatest Reward Is Changing Lives, Not Winning Awards
-
Oct 16, 2026, 15:18Carmine Liberatore: Limited Accuracy of VTE Risk Scores in Multiple Myeloma
-
Oct 16, 2026, 14:55Alex Borstein and the Bleeding Phenotype of Hemophilia A Carriers