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Antonio Sorropago: Major Updates in Structural Heart Interventions
Antonio Sorropago/LinkedIn
Aug 31, 2026, 16:02

Antonio Sorropago: Major Updates in Structural Heart Interventions

Antonio Sorropago, Interventional Cardiologist at Policlinico di Monza, shared a post on LinkedIn about a recent articles, adding:

“Updates in structural heart interventions just dropped at HOTLINE 7 ESCCongress

From optimizing post TAVI antithrombotic strategies to game changing T TEER  Key takeaways and links to full papers

POPular ACE TAVI: Routine protamine administration after TAVI safely and significantly reduces the 30 day composite risk of mortality and bleeding compared to a selective approach, a benefit driven almost entirely by the prevention of minor Type 1 bleeds

TAVI PCI: For patients needing both TAVI and revascularization, performing TAVI first is noninferior to PCI first strategy at 1 year, validating a flexible valve first procedural sequence

TRIC I HF: In patients with severe tricuspid regurgitation and advanced heart failure, T TEER significantly improves 1 year QoL and clinical outcomes while slashing 3 year death or HF hospitalizations by 60 percent compared with OMT alone

ACASA TAVI: Twelve months of DOAC monotherapy after TAVI cuts subclinical leaflet thrombosis nearly in half compared with aspirin alone without compromising safety for bleeding, thromboembolic events or death

NOTION 4: A short 3 month DOAC regimen after TAVI only temporarily suppresses leaflet thickening on treatment showing no lasting prevention at 1 year and a higher composite risk of death, stroke or major bleeding compared with single antiplatelet therapy”

Title 1: Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation

Authors: Barbara E. Stähli, Frank Ruschitzka, Dirk Westermann, Axel Linke, Norman Mangner, Nicolas M. Van Mieghem, Rahel Kesterke, Laura Oberholzer, Jürgen Rothe, Constantin von zur Mühlen, Tobias Zeus, Won-Keun Kim, Philipp Lauten, Nikos Werner, Christof Burgdorf, Hannes Alber,  P. Christian Schulze, Michael Joner, Jonathan Michel, Alessandro Candreva, Philipp Jakob, Michael Würdinger, Julia Stehli, Alexander Gotschy, Christian Templin, Omer Dzemali, Luise Gaede, Steffen Massberg, Alexander Lauten, Frank van der Kley, Aydan Ewers, Thomas Nestelberger, Mohamed Abdel-Wahab, Giuseppe Musumeci, Sebastian Barth, Michael Hansen, Andreas Mügge, Moritz Seiffert, David M. Leistner, Thomas Cuisset, Steffen Schneider, Adnan Kastrati, Ian Ford, Markus A. Kasel

Read the Full Article on The New England Journal of Medicine

Antonio Sorropago: Major Updates in Structural Heart Interventions

Title 2: Tricuspid Valve Intervention in Heart Failure

Authors: Jörg Hausleiter, Thomas J. Stocker, Tobias Geisler, Philipp Lurz, Wolfgang Rottbauer, Edith Lubos, Niklas Schofer, Christian Frerker,  Johanne Frank, Holger Thiele, Rico Osteresch, Volker Rudolph, Alexander Lauten, Erion Xhepa,  Jürgen Rothe, Tienush Rassaf, Stephan Baldus, Georg Nickenig, David M. Leistner, Eike Tigges, Victoria Kehl, Mirjam Kessler, Tobias Kister, Tobias Ruf, Muhammed Gerçek, Meinrad Gawaz, Derk Frank, Ingo Eitel, Ralph Stephan von Bardeleben, Daniel Kalbacher, Osama Soliman, Michael Näbauer, Steffen Massberg

Read the Full Article on The New England Journal of Medicine

Antonio Sorropago: Major Updates in Structural Heart Interventions

Title 3: Anticoagulation Monotherapy vs Antiplatelet Monotherapy After Transcatheter Aortic Valve ImplantThe ACASA-TAVI Randomized Clinical Trial

Authors: Christopher S. Dodgson, Jon Herstad, Sophie F. Kløve, Malin Flygel, Mehdi Akhavi, Sverre Høie, Jan Otto Beitnes, Christian H. Eek, Kaspar Broch, Céline Cunen, Lars Gullestad,  Lars Aaberge, Ketil Lunde, Bjørn Bendz, Øyvind H. Lie

Read the Full Article on JAMA

Antonio Sorropago: Major Updates in Structural Heart Interventions

Title 4: Short-Term Anticoagulant Therapy and Subclinical Leaflet Thickening in Transcatheter Aortic Valves: The NOTION-4 Trial

Authors 4:  Troels Højsgaard Jørgensen, Andreas Fuchs Larsen, Jesper Møller Jensen, Rebekka Vibjerg Jensen, Yannick Willemen, Aekapat Phoksiri, Arif Khokhar, Jani Thuraiaiyah, Kamilla Bech Pedersen, Gintautas Bieliauskas, Christian Juhl Terkelsen, Lars Søndergaard, Klaus Fuglsang Kofoed, Bjarne Linde Nørgaard, and Ole De Backer

Read the Full Article on JACC Journals.

Antonio Sorropago: Major Updates in Structural Heart Interventions

Stay updated on all scientific advances with Hemostasis Today.

Adnan Kastrati Aekapat Phoksiri Alessandro Candreva Alexander Gotschy Alexander Lauten Andreas Fuchs Larsen Andreas Mügge Antonio Sorropago Arif Khokhar Axel Linke Aydan Ewers Barbara E. Stähli Bjarne Linde Nørgaard Bjørn Bendz Céline Cunen Christian H. Eek Christian Juhl Terkelsen Christian Templin Christof Burgdorf Christopher S. Dodgson Constantin von zur Mühlen David M Leistner Dirk Westermann Frank Ruschitzka Frank van der Kley Gintautas Bieliauskas Giuseppe Musumeci Hannes Alber Health Hematology Hemostasis Hemostasis News Hemostasis Today Ian Ford Jan Otto Beitnes Jani Thuraiaiyah Jesper Møller Jensen Jon Herstad Jonathan Michel Julia Stehli Jürgen Rothe Kamilla Bech Pedersen Kaspar Broch Ketil Lunde Klaus Fuglsang Kofoed Lars Aaberge Lars Gullestad Lars Søndergaard Laura Oberholzer Luise Gaede Malin Flygel Markus A. Kasel Medicine Mehdi Akhavi Michael Hansen Michael Joner Michael Würdinger Mohamed Abdel-Wahab Moritz Seiffert Nicolas M. van Mieghem Nikos Werner Norman Mangner Ole de Backer Omer Dzemali Øyvind H. Lie P Christian Schulze Philipp Jakob Philipp Lauten Rahel Kesterke Rebekka Vibjerg Jensen Sebastian Barth Sophie F. Kløve Steffen Massberg Steffen Schneider Sverre Høie Thomas Cuisset Thomas Nestelberger Tobias Zeus Troels Højsgaard Jørgensen Won-Keun Kim Yannick Willemen
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