Christophe Vandenbriele: Bleeding on VA-ECMO Remains the Achilles’ Heel
Christophe Vandenbriele, Research and Clinical Consultant at Royal Brompton and Harefield hospitals, shared on LinkedIn about a recent article he and his colleagues co-authored, adding:
“Have a look at our new ECMO bleeding study – published in Critical Care
Bleeding on VA-ECMO: still the Achilles’ heel
New data from a large, Dutch (n=6) multicenter cohort:
Clinical correlates for major bleeding during VA-ECMO
Key points:
- 42% of patients experienced major bleeding
- Most events occur early (<48h)
- Bleeding, higher ICU mortality
- Risk is dynamic, not static, lab trends matter
Take-home:
We should move beyond fixed anticoagulation targets and toward dynamic, individualized bleeding risk assessment.
Congratulations Christiaan Meuwese!”
Title: Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective
Authors: Lara C. A. Pladet, Hassnae Boubrik, Kim Luijken, Carlos V. Elzo Kraemer, Jacinta J. Maas, Jeroen J. H. Bunge, Myrthe P. J. van Steenwijk, Erik Scholten, Leon J. Montenij, Laurien van Koppenhagen, Nicole P. Juffermans, Alexander P. J. Vlaar, Walter M. van den Bergh, Robert J. van Thiel, Karen C. Bokhoven, Christoph Vandenbriele, Nicolas M. van Mieghem, Olaf L. Cremer, Dirk W. Donker, Dimitris Rizopoulos, Christiaan L. Meuwes
Read the Full Article on Critical Care

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