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Christophe Vandenbriele: Bleeding on VA-ECMO Remains the Achilles’ Heel
Christophe Vandenbriele/www.phdcup.be; Christiaan Meuwese/LinkedIn
Mar 29, 2026, 12:00

Christophe Vandenbriele: Bleeding on VA-ECMO Remains the Achilles’ Heel

Christophe Vandenbriele, Research and Clinical Consultant at Royal Brompton and Harefield hospitals, shared on LinkedIn about a recent article he and his colleagues co-authored, adding:

“Have a look at our new ECMO bleeding study – published in Critical Care

Bleeding on VA-ECMO: still the Achilles’ heel

New data from a large, Dutch (n=6) multicenter cohort:

Clinical correlates for major bleeding during VA-ECMO

Key points:

  • 42% of patients experienced major bleeding
  • Most events occur early (<48h)
  • Bleeding, higher ICU mortality
  • Risk is dynamic, not static, lab trends matter

Take-home:

We should move beyond fixed anticoagulation targets and toward dynamic, individualized bleeding risk assessment.

Congratulations Christiaan Meuwese!”

Title: Clinical correlates for major bleeding during veno-arterial extracorporeal membrane oxygenation support: a time-dependent perspective

Authors: Lara C. A. Pladet, Hassnae Boubrik, Kim Luijken, Carlos V. Elzo Kraemer, Jacinta J. Maas, Jeroen J. H. Bunge, Myrthe P. J. van Steenwijk, Erik Scholten, Leon J. Montenij, Laurien van Koppenhagen, Nicole P. Juffermans, Alexander P. J. Vlaar, Walter M. van den Bergh, Robert J. van Thiel, Karen C. Bokhoven, Christoph Vandenbriele, Nicolas M. van Mieghem, Olaf L. Cremer, Dirk W. Donker, Dimitris Rizopoulos, Christiaan L. Meuwes

Read the Full Article on Critical Care

Christophe Vandenbriele: Bleeding on VA-ECMO Remains the Achilles' Heel

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Alexander P. J. Vlaar Carlos V. Elzo Kraemer Christiaan L. Meuwes Christoph Vandenbriele Critical Care Dimitris Rizopoulos Dirk W. Donker ECMO Erik Scholten Hassnae Boubrik Health Hematology Hemostasis Hemostasis News Hemostasis Today Jacinta J. Maas Jeroen J. H. Bunge Karen C. Bokhoven Kim Luijken Lara C. A. Pladet Laurien van Koppenhagen Leon J. Montenij Medicine Myrthe P. J. van Steenwijk Nicolas M. van Mieghem Nicole P. Juffermans Olaf L. Cremer Robert J. van Thiel VA-ECMO Walter M. van den Bergh
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