Intensive Clotting Factor Prophylaxis Does Not Prevent Severe PPH in VWD – JTH
Journal of Thrombosis and Haemostasis (JTH) shared on LinkedIn about a recent article by Anne de Vaan et al, adding:
”Higher-Dosed Clotting Factor Prophylaxis Fails to Reduce Postpartum Hemorrhage in Women With von Willebrand Disease
A prospective Dutch study found that intensified prophylactic clotting factor therapy during pregnancy did not reduce severe postpartum hemorrhage rates in women with von Willebrand disease.”
Title: Higher-dosed clotting factor prophylaxis fails to reduce postpartum hemorrhage in women with von Willebrand disease: findings from the observational PRegnancy and Inherited bleeding DisordErS study
Authors: Anne de Vaan, Jeroen Eikenboom, Marieke Kruip, Marieke Punt, Saskia Schols, Floor Heubel-Moenen, Michiel Coppens, Laurens Nieuwenhuizen, Anja Mäkelburg, Marjolein Peters, Hans Duvekot, Annemieke Middeldorp, Kitty Bloemenkamp, Roger Schutgens, Titia Lely, Karin van Galen
Read the Full Article on JTH

Stay updated on all scientific advances with Hemostasis Today.
-
Jul 23, 2026, 10:33Johanna Rodríguez: The Structural Challenge of Next-Gen Anticoagulants
-
Jul 23, 2026, 10:27Logan Hamilton: New Study Identifies the Mutated Antibody Gene Responsible for VITT
-
Jul 23, 2026, 09:05Fonkou Steve: What If We’ve Been Asking the Wrong Question About Plasma Too?
-
Jul 23, 2026, 08:27Registration Is Now Open for ASH 2026
-
Jul 23, 2026, 08:19Sheeza Nawaz: Why Do Patients With Aortic Stenosis Bleed?
-
Jul 23, 2026, 07:59Paschalis Karakasis: Can Left Atrial Appendage Closure Truly Replace Oral Anticoagulation?
-
Jul 23, 2026, 06:53Lakmali Silva: What Makes ISTH More Than a Scientific Meeting?
-
Jul 23, 2026, 05:48Paschalis Evangelidis: Rethinking Pulmonary Embolism Through the Lens of Thromboinflammation
-
Jul 23, 2026, 05:35Neil Morgan: Honoured to Lead the Platelet and Megakaryocyte Theme at ISTH 2026