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August, 2026
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Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure
Aug 27, 2026, 14:26

Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure

Davide Capodanno, Full Professor of Cardiology at the University of Catania, shared a post on LinkedIn about recent articles, published in JAMA Cardiology, adding:

“No free lunch.

In our meta-analysis, now published in JAMA Cardiology, transcatheter left atrial appendage closure (LAAC) was associated with similar long-term risks of any stroke and major bleeding compared with oral anticoagulation in patients with atrial fibrillation, while increasing the risk of ischemic stroke and reducing the risk of nonprocedure-related major bleeding.”

Title: Catheter-Based Left Atrial Appendage Closure vs Oral Anticoagulation in Patients With Atrial FibrillationA Systematic Review and Meta-Analysis

Authors: Claudio Laudani, Kamil Bujak, Daniele Giacoppo, Simone Finocchiaro, Luigi Cutore, Maria Sara Mauro, Pietro Redigolo, Placido Maria Mazzone, Giacinto Di Leo, Francesco Nasisi, Marco Spagnolo, Antonio Greco, Davide Capodanno

Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure

Title: Left Atrial Appendage Occlusion vs Oral Anticoagulation—No Free Lunch

Authors: Jonathan P. Piccini

Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure

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