Jamie Nash: Microfluidics in Transfusion Medicine Advancing Blood Component Quality Assessment
Jamie Nash, Postdoctoral Research Scientist at Welsh Blood Service, Member of UK Young Academy, shared a post on LinkedIn about a recent article by E. J. Sayers et al, published in Wiley Online Library, adding:
“New Publication
Our review, Microfluidics to Assess the Impact of Transfused Blood Components, highlights current applications of microfluidic technologies in assessing blood component quality.
The review focuses on red blood cells, platelets, and plasma, and explores how these innovative approaches are helping move the field toward more physiologically relevant systems for evaluating component quality.
What is known about the topic?
Current haemostasis measurements fail to take in to account physiological flow limiting in vivo correlation.
Microfluidics can simulate vascular environments and make observations of blood components.
What is new?
Microfluidics can be used to assess novel transfusion components (such as cold stored platelets).
Integration with organ on a chip allows for transfusion related pathology analysis.
What are the key questions for future work?
How can microfluidics be standardised to create comparable analysis platforms?
How can microfluidics be better used to model organ function, e.g. splenic or hepatic clearance of transfusion components?”
Title: Microfluidics to assess the impact of transfused blood components
Authors: E. J. Sayers, J. Nash, E. M. Davies, C. V. Saunders, C. E. George
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