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Jason Andrade: SINGLE-AF Trial Validates Early Anticoagulation in AF
Aug 31, 2026, 14:14

Jason Andrade: SINGLE-AF Trial Validates Early Anticoagulation in AF

Jason Andrade, Clinical Professor at The University of British Columbia, shared a post on LinkedIn:

“This is an incredibly important study.

The just presented SINGLE-AF trial randomised patients with a single risk factor (other than sex), demonstrating a significant reduction in stroke, systemic embolism, major bleeding, or death from cardiovascular causes at 24 months.

Although the SCC CCS AF guidelines have advocated for OAC for this group of patients for many years, sometimes at contrast with other national societies, its nice to see that this approach has been validated in a large RCT.”

Oussama Wazni, Vice Chair of CVM, Section Head of Cardiac EP at Cleveland Clinic, shared this post on LinkedIn, adding:

“Yes Jason, a very important study indeed and in line with our thinking for anticoagulation in this group.”

Title: Anticoagulation for Atrial Fibrillation with Intermediate Stroke Risk

Authors: Daehoon Kim, Young Soo Lee, Jaemin Shim, Hee Tae Yu, Junbeom Park, Jin-Kyu Park, Il-Young Oh, Ki-Woon Kang, Eue-Keun Choi, Kyoung-Min Park, Hyoung-Seob Park, Dae-Hyeok Kim, Hyung Wook Park, Jun Kim, Jum-Suk Ko, Dongmin Kim, Jong-Youn Kim, Jin-Bae Kim, Jung-Hoon Sung, Tae-Hoon Kim, Jae-Sun Uhm, Hui-Nam Pak, Boyoung Joung

Jason Andrade

Title: The 2020 Canadian Cardiovascular Society/Canadian Heart Rhythm Society Comprehensive Guidelines for the Management of Atrial Fibrillation

Authors: Jason G. Andrade, Martin Aguilar, Clare Atzema, Alan Bell, John A. Cairns, Christopher C. Cheung, Jafna L. Cox, Paul Dorian, David J. Gladstone, Jeff S. Healey, Paul Khairy, Kori Leblanc, M. Sean McMurtry, L. Brent Mitchell, Girish M. Nair, Stanley Nattel, Ratika Parkash, Louise Pilote, Roopinder K. Sandhu, Jean-François Sarrazin, Mukul Sharma, Allan C. Skanes, Mario Talajic, Teresa S.M. Tsang, Atul Verma, Subodh Verma, Richard Whitlock, D. George Wyse, Laurent Macle

Jason Andrade: SINGLE-AF Trial Validates Early Anticoagulation in AF

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