JTH: New Data Exposes Wide Variation in U.S. Perioperative Bleeding Management
Journal of Thrombosis and Haemostasis (JTH) posted on LinkedIn:
”Perioperative use of factor concentrates and blood products – a survey of clinical practices in the United States
By Jerrold Levy, Joseph R. Shaw, Kamrouz Ghadimi, Cheryl Maier, Douketis James, Keyvan Karkouti, Michael Mazzeffi, Alex C Spyropoulos, MD, FACP, FCCP, FRCPC, Kenichi Tanaka, Jean Connors, and Roman Sniecinski
The management of perioperative bleeding and anticoagulant reversal is rapidly evolving, shaped by new education initiatives and expanding availability of factor concentrates.
4-factor PCCs were the preferred therapy for warfarin and DOAC reversal in emergency surgery and major bleeding (used by >70%).
Cryoprecipitate remained the dominant source of fibrinogen replacement (66%), while access to fibrinogen concentrate was limited.
FFP continued as the first-line product for factor replacement in cardiac (60%), hepatic (67%), and postpartum hemorrhage (71%).
These data show a steady shift toward PCC-centric reversal strategies, with persistent heterogeneity in fibrinogen replacement and factor support across US perioperative settings.
Read the article here.”
Title: Perioperative use of factor concentrates and blood products—a survey of clinical practices in the United States: communication from the ISTH Subcommittee on Perioperative and Critical Care
Authors: Jerrold H. Levy, Joseph R. Shaw, Kamrouz Ghadimi, Cheryl L. Maier, James Douketis, Keyvan Karkouti, Michael Mazzeffi, Alex C. Spyropoulos, Kenichi A. Tanaka, Jean M. Connors, Roman M. Sniecinski
Stay updated with Hemostasis Today.
-
Dec 15, 2025, 15:58Khaled Musallam Applauds Hatoon Ezzat’s Leadership and Healthcare Advances in Saudi Arabia
-
Dec 15, 2025, 12:46Deborah Ebert Long on Hemophilia Care: Progress, Possibility, and the Power of Listening
-
Dec 15, 2025, 12:34Nathan Connell on Conversion from Eptacog Alfa to Beta
-
Dec 15, 2025, 12:17Danny Hsu on Interdisciplinary Toolkit for Gynecologic Bleeding on Anticoagulation
-
Dec 15, 2025, 12:08Ted Roh: A Historic Milestone for Indonesia’s Health Innovation
-
Dec 15, 2025, 11:28Wolfgang Miesbach Shares Insights from Davide Matino’s Presentation on Marstacimab at ASH25
-
Dec 15, 2025, 11:12Tushar Pandey Awarded for His Enourmous Contribution to Hematology
-
Dec 15, 2025, 11:07DISTRO: Vidya Rajbhoj on AI and Digital Technology to Improve Stroke Rehabilitation
-
Dec 15, 2025, 11:00Ischemic Stroke, AF and Atherosclerotis: Amira Khater on Sufficiency of Anticoagulant Monotherapy