JTH: New Data Exposes Wide Variation in U.S. Perioperative Bleeding Management
Journal of Thrombosis and Haemostasis (JTH) posted on LinkedIn:
”Perioperative use of factor concentrates and blood products – a survey of clinical practices in the United States
By Jerrold Levy, Joseph R. Shaw, Kamrouz Ghadimi, Cheryl Maier, Douketis James, Keyvan Karkouti, Michael Mazzeffi, Alex C Spyropoulos, MD, FACP, FCCP, FRCPC, Kenichi Tanaka, Jean Connors, and Roman Sniecinski
The management of perioperative bleeding and anticoagulant reversal is rapidly evolving, shaped by new education initiatives and expanding availability of factor concentrates.
4-factor PCCs were the preferred therapy for warfarin and DOAC reversal in emergency surgery and major bleeding (used by >70%).
Cryoprecipitate remained the dominant source of fibrinogen replacement (66%), while access to fibrinogen concentrate was limited.
FFP continued as the first-line product for factor replacement in cardiac (60%), hepatic (67%), and postpartum hemorrhage (71%).
These data show a steady shift toward PCC-centric reversal strategies, with persistent heterogeneity in fibrinogen replacement and factor support across US perioperative settings.
Read the article here.”
Title: Perioperative use of factor concentrates and blood products—a survey of clinical practices in the United States: communication from the ISTH Subcommittee on Perioperative and Critical Care
Authors: Jerrold H. Levy, Joseph R. Shaw, Kamrouz Ghadimi, Cheryl L. Maier, James Douketis, Keyvan Karkouti, Michael Mazzeffi, Alex C. Spyropoulos, Kenichi A. Tanaka, Jean M. Connors, Roman M. Sniecinski
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