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Kemal Karaagac: Milvexian Did Not Reduce Ischemic Events but Did Not Increase Fatal Bleeding
Kemal Karaagac/LinkedIn
Aug 31, 2026, 16:55

Kemal Karaagac: Milvexian Did Not Reduce Ischemic Events but Did Not Increase Fatal Bleeding

Kemal Karaagac, Cardiologist at Cihangir Hospital, shared a post on X about a recent article by C. Michael Gibson et al., published in NEJM, adding:

“Among patients with a recent ACS event, Milvexian that factor XI inhibitor, did not decrease the risk of death, myocardial infarction, or ischemic stroke but did not increase the risk of intracranial or fatal bleeding, as compared with placebo.”

Title: Milvexian with Antiplatelet Therapy after Acute Coronary Syndrome Event

Authors: C. Michael Gibson, P. Gabriel Steg, M. Cecilia Bahit, Rasha Al-Lamee, Shamir R. Mehta, Roxana Mehran, Jeffrey I. Weitz, Shinya Goto, Jose Carlos Nicolau, Renato D. Lopes, Junbo Ge, Nebojsa Tasic, Dominick J. Angiolillo, Suzanne J. Baron, Ajay J. Kirtane, Denis Xavier, Satoshi Yasuda, Basil S. Lewis, Duk-Woo Park, Jan H. Cornel, Thomas W. Johnson, Jaroslaw Trebacz, Daniel Duerschmied, Christoph Bode, Bela Merkely, Maria Dorobantu, Dragos Vinereanu, Zuzana Motovska, Hector Bueno, Jose Luis Lopez-Sendon, Gregory Ducrocq, Giuseppe Ambrosio, Lesley Burgess, Allan Bohm, Chern-En Chiang, Joao Morais, Alan Fong, Umit Guray, Jose Luis Leiva-Pons, Pascal Vranckx, Harvey D. White, Sasko Kedev, Marco Valgimigli, Duško Cerovec, Dimitris Tousoulis, Gemma Figtree, Thuong Dung Ho, Rody G. Sy, Morten Bøttcher, Kurt Huber, Rimvydas Slapikas, Andrejs Erglis, Jack Wei Chieh Tan, Christian Pincetti, Karen S. Pieper, Kenneth W. Mahaffey, Carolyn S.P. Lam, S. Claiborne Johnston, Graeme J. Hankey, Luke Zheng, Ronald Aronson, Danshi Li, Ravi Notani, Philippe Vieira Pires, Thomas J. Povsic, Alistair C. Lindsay, Alexei Plotnikov, Hsiaowei Deng, Elliot S. Barnathan, Robert A. Harrington

Kemal Karaagac

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ACS Ajay J. Kirtane Alan Fong Alexei Plotnikov Alistair C. Lindsay Allan Bohm Andrejs Erglis Anticoagulation Basil S. Lewis Bela Merkely bleeding disorders Blood C. Michael Gibson Cardiology Carolyn S.P. Lam Chern-En Chiang Christian Pincetti Christoph Bode Daniel Duerschmied Danshi Li Denis Xavier Dimitris Tousoulis Dominick J. Angiolillo Dragos Vinereanu Duk-Woo Park Duško Cerovec Elliot S. Barnathan Factor XI Factor XI Inhibitors Gemma Figtree Giuseppe Ambrosio Graeme J. Hankey Grégory Ducrocq Harvey D. White Health Hector Bueno Hematology Hemostasis Hemostasis News Hemostasis Today Hsiaowei Deng Ischemic stroke Jack Wei Chieh Tan Jan H. Cornel Jaroslaw Trebacz Jeffrey I. Weitz Joao Morais Jose Carlos Nicolau Jose Luis Leiva-Pons Jose Luis Lopez-Sendon Junbo Ge Karen S. Pieper Kemal Karaagac Kenneth W. Mahaffey Kurt Huber Lesley Burgess Luke Zheng M. Cecilia Bahit Marco Valgimigli Maria Dorobantu Medicine milvexian Morten Böttcher Myocardial infarction Nebojsa Tasic NEJM P. Gabriel Steg Pascal Vranckx Philippe Vieira Pires Rasha Al-Lamee Ravi Notani Renato D. Lopes Rimvydas Slapikas Robert A. Harrington Rody G. Sy Ronald Aronson Roxana Mehran S Claiborne Johnston Sasko Kedev Satoshi Yasuda Shamir R. Mehta Shinya Goto stroke Suzanne J. Baron Thomas J. Povsic Thomas W. Johnson Thuong Dung Ho Umit Guray Zuzana Motovska
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