Leo Nicolai and Rainer Kaiser Link Procoagulant Platelets and Thromboinflammation in CVD
Leo Nicolai, Physician-Researcher in Cardiology at Medizinische Klinik und Poliklinik I, LMU Klinikum München, shared on LinkedIn:
”Happy to share Rainer Kaiser‘s and my review about procoagulant platelets in cardiovascular disease just published in Nature Reviews Cardiology’‘
Platelets play a central role in haemostasis following vascular injury and are essential for thrombus formation.
Beyond aggregation and clot contraction, platelets can enter a distinct, highly activated procoagulant state that contributes to the development of cardiovascular diseases such as myocardial infarction, stroke, and deep vein thrombosis, and links thrombosis with inflammation.
This Review examines recent advances in understanding procoagulant platelets, including their role in macrovascular and microvascular clot formation and the key receptors and signalling pathways that define this activation state.
It also discusses the clinical relevance of procoagulant platelet activation and explores existing and emerging therapeutic strategies that may enable new diagnostic and treatment approaches for cardiovascular, inflammatory, and immune-mediated diseases.
Read the full article in Nature Reviews Cardiology.
Article: Procoagulant platelets: linking coagulation and thromboinflammation in cardiovascular disease
Authors: Rainer Kaiser, Leo Nicolai
Stay updated on all scientific advances with Hemostasis Today.
-
Jan 14, 2026, 16:01Renato Simonetti Presents a Pilot Project on AI-assisted Duplex Sonography for ICH
-
Jan 14, 2026, 15:47An Unusual Case from Mohammed Ameen: Unexpected Clot Unmasking Antithrombin III Deficiency
-
Jan 14, 2026, 11:38Khokon Miah Akanda Shares A major 4-Guideline Comparison on BP Management in Stroke
-
Jan 14, 2026, 11:26Pablo Albasanz-García and Colleagues on Anticancer Treatment-Induced Arterial and Venous Thrombosis
-
Jan 14, 2026, 11:16ISTH 2026: Laurent Bertoletti To Serve as Vice Theme Leader for VTE
-
Jan 14, 2026, 11:08Leni von Bonsdorff Invites You to Hear and Learn The Latest News in The Plasma Field
-
Jan 14, 2026, 05:56Arun V J on The “Whole Blood” Nostalgia Trap
-
Jan 13, 2026, 16:38Caitlin Raymond: Understanding TAMOF as a TTP-Like Process
-
Jan 13, 2026, 15:22John Amako: Childhood to Adulthood Management Approach for SCD