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Lucas Di Meglio and Team Show That Targeting Extracellular DNA Mayy Reduce Microvascular Thrombosis
Lucas Di Meglio/LinkedIn
Nov 25, 2025, 10:14

Lucas Di Meglio and Team Show That Targeting Extracellular DNA Mayy Reduce Microvascular Thrombosis

RPTH Journal shared on LinkedIn:

”Can DNase 1 protect the brain after stroke?

New research from Lucas Di Meglio and team shows that targeting extracellular DNA may reduce microvascular thrombosis and improve outcomes.

Want to see how DNase 1 changed the game in experimental stroke models?

Co-Authors: Mialitiana Solo Nomenjanahary, Laurine Bedoucha, sebastien dupont, Fatima Zemali, Veronique Olliver, Clement Journe, Martine Jandrot Perrus, Thomas Rambaud, Mikael Mazighi, Benoit Ho-Tin-Noe, Jean-Philippe Desilles”

Read the full article here.

Article: Neutrophil extracellular traps-targeting therapy with deoxyribonuclease 1 reduces large vessel occlusion-induced downstream microvascular thromboinflammation in a rat model of stroke

Authors: Lucas Di Meglio, Mialitiana Solo Nomenjanahary, Laurine Bedoucha, Sebastien Dupont, Fatima Zemali, Véronique Ollivier, Clement Journe, Martine Jandrot-Perrus, Thomas Rambaud, Mikael Mazighi, Benoit Ho-Tin-Noe, Jean-Philippe Desilles

Lucas Di Meglio and Team Show That Targeting Extracellular DNA Mayy Reduce Microvascular Thrombosis

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Benoit Ho-Tin-Noe Clement Journe DNase 1 extracellular DNA Fatima Zemali Health Hematology Hemostasis Hemostasis Today Jean-Philippe Desilles Laurine Bedoucha Lucas Di Meglio Martine Jandrot-Perrus Medicine Mialitiana Solo Nomenjanahary microvascular thrombosis Mikael Mazighi rpth Sebastien Dupont stroke Thomas Rambaud thrombosis Véronique Ollivier
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