Spiros Denaxas: National Linked Health Records Reveal Stroke Care Gaps England During and After COVID-19
Spiros Denaxas, Professor of Biomedical Informatics at UCL, shared on LinkedIn about a recent article he and his colleagues co-authored, published in BMJ Open, adding:
”Excited to share our new paper in BMJ Open led by James Farrell and William Whiteley, a national study of stroke care quality using linked electronic health records across England during and after the COVID-19 pandemic.
We linked SSNAP, primary care (GDPPR), hospital admissions (HES), dispensed medications (NHSBSA) and mortality records for 425,675 adults with a first stroke (2020–2023) via NHS England’s Secure Data Environment.
Key findings:
- Combining all data sources captured strokes missed by any single source alone — 10.8% of non-fatal ischaemic strokes appeared only in primary care, and 19.4% of fatal strokes only in death records.
- Standardised stroke incidence rose from 228 to 245 per 100,000 over the study period, with COVID-19 lockdowns shifting cases from healthcare encounters to deaths.
- Secondary prevention gaps persist: while ~89% of ischaemic stroke patients received antithrombotic therapy, only 44.5% were dispensed antihypertensives — a pattern driven by age and comorbidity, not the pandemic.
- ‘Home-time’ (days alive and out of hospital in 180 days post-stroke) proved a sensitive, person-centred outcome metric, exposing disparities by deprivation, severity and region.”
Title: Measurement of quality of stroke care with national electronic health records: a prospective cohort study during and after the COVID-19 pandemic
Authors: James Farrell, John Nolan, Roger Lambert, Ana Torralbo, Steffen E Petersen, Mevhibe Hocaoglu, Chris Tomlinson, Reecha Sofat, Qi Huang, Evan Kontopantelis, Martin James, Sarah Lessels, Jacqueline A L MacArthur, Angela M Wood, William N Whiteley, Spiros Denaxas

Stay updated on all scientific advances with Hemostasis Today.
-
Aug 27, 2026, 11:08Sunisha Arora: New EBMT Recommendations Transform the Approach to HSCT in Thalassemia
-
Aug 27, 2026, 10:51Seema Dawood: A Layered Approach to Identifying Thalassemia in the Laboratory
-
Aug 27, 2026, 10:44Ed Smith: Vitalant Expands Hemophilia Center Team With New Career Opportunities
-
Aug 27, 2026, 10:43FDA Expands Hympavzi Approval to Children and Patients With Hemophilia A or B With Inhibitor
-
Aug 27, 2026, 10:28Narat Srivali: Exploring the Link Between Perioperative Corticosteroids and VTE Risk
-
Aug 27, 2026, 10:19Vincent Poher: Clinical Validation of Rapid Whole-Blood Fibrinogen Measurement
-
Aug 27, 2026, 07:49Denis Oduor: Bringing Blood Closer – Strengthening Kenya’s Response to PPH
-
Aug 27, 2026, 07:19Luis Oliverio Ambriz Garcia: ASH 2026 Guidelines – What’s New in ITP?
-
Aug 27, 2026, 06:58Priyam Bordoloi: The Biological Advantage of Two X Chromosomes