Umberto Pensato: EVT Treatment Effects Across Perfusion Profiles in MeVO Stroke
Umberto Pensato, Assistant Professor of Neurology at the Humanitas University, Research Collaborator at the University of Calgary, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in JAMA Network Open, adding:
”Our post-hoc analysis of the ESCAPE-MeVO trial explores the treatment effect of EVT vs. best medical therapy in acute stroke due to MeVO across perfusion mismatch profiles, now published in JAMA Network Open.
The results were perhaps unexpected for me, with no clear treatment-effect modification across perfusion profiles (though perhaps a signal for penumbral volume more than 30 mL?).
The quest to find ‘green flags’ to identify MeVO patients who benefit from EVT is still on going (favorable imaging, early time, and high NIHSS most promising so far)
Extremely grateful to Johanna Ospel, Michael Hill, Mayank Goyal and the full ESCAPE-MeVO group for the opportunity and their support.”
Title: Thrombectomy for Acute Stroke Due to Medium Vessel Occlusion Across Perfusion Mismatch ProfilesA Post Hoc Analysis of the ESCAPE-MeVO Trial
Authors: Umberto Pensato, Gunjan Jindal, William Diprose, Aravind Ganesh, Pattarawut Charatpangoon, Ethan MacDonald, Alexander Stebner, Salome Bosshart, Dar Dowlatshahi, David Volders, James Kennedy, Markus Möhlenbruch, Brian H. Buck, Shahid Nimjee, Thomas Booth, Mouhammad Jumaa, Jai J. Shankar, Franziska Dorn, Andrew M. Demchuk, Mayank Goyal, Michael D. Hill, Johanna M. Ospel
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 15, 2026, 18:26Chanakya Nayudu: Presenting My Research at ISTH Congress 2026 in Paris
-
Oct 15, 2026, 18:09Maha Othman: Students Lead World Thrombosis Day 2026 Awareness Events
-
Oct 15, 2026, 17:52Jill de Mol։ Rapamycin Modulates Immune Responses in Aged Atherosclerosis
-
Oct 15, 2026, 17:41Victor Aboyans։ Think About Lipids in VTE
-
Oct 15, 2026, 17:08Babu Mia։ Targeting PPM1D to Eliminate Malignant Stem Cells in Myeloproliferative Neoplasms
-
Oct 15, 2026, 16:26Hauke Horstmann: Can an Existing Drug Be Repurposed to Treat Atherosclerosis?
-
Oct 15, 2026, 15:19Bernadette Borrelli: AdventHealth Teams Unite to Mark World Thrombosis Day
-
Oct 15, 2026, 15:03Mohamed Magdy: The Hematological Consequences of Portal Hypertension in Banti Syndrome
-
Oct 15, 2026, 14:34Marium Khan: New Systematic Review Examines Asundexian Safety and Efficacy in Cardiovascular Disease