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Leigh Anne Siino on The Spherix Global’s Translation of ASH25 Insights Into Actionable Intelligence
Leigh Anne Siino/LinkedIn
Dec 23, 2025, 12:56

Leigh Anne Siino on The Spherix Global’s Translation of ASH25 Insights Into Actionable Intelligence

Leigh Anne Siino, Chief Revenue Officer at Spherix Global Insights, shared on LinkedIn:

”The Spherix Global Insights Hematology/Oncology team is translating key insights from ASH25 into actionable intelligence — helping strategy, commercial, and medical teams across pharma prepare for the next wave of change across benign and malignant hematology.

What we’re seeing and why it matters now:

Sickle Cell Disease: Turning Patient Voice and Data Into Advantage

SCD is entering a pivotal period, with growing emphasis on coordinated patient-level data and deeper incorporation of patient perspectives.

As pipelines advance and treatment options expand, organizations with timely, centralized insights will be best positioned to optimize targeting, prepare for launches, and align strategies with real-world care delivery.

Cross-Therapeutic Mechanisms and Gene Therapy in Benign Hematology

ASH underscored rising interest in therapies with shared mechanisms across conditions — including autoimmune cytopenias, SCD, hemophilia, and vWD — alongside continued focus on gene therapies.

These dynamics reinforce the need for cross-therapy intelligence to support faster, evidence-based decision-making as indications evolve.

Malignant Hematology: Next-Gen Modalities and Earlier-Line Opportunity

In malignant disease, advances in CAR-T platforms, expanding AML pipelines, and movement into earlier lines (including smoldering multiple myeloma) are reshaping both clinical and commercial landscapes.

Explore our latest and upcoming hematology publications on the Spherix Client Portal.”

All from ASH25 featured in Hemostasis Today.

ASH2025 ASH25 bleeding disorders CAR-T Gene therapy Health Hematology Hemophilia Hemostasis Hemostasis Today Leigh Anne Siino Medicine SCD Spherix Global VWD
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