Hemostasis Today
NewsFeed
Headlines Hematology Health Medicine VTE ASH Plasma Donation
April, 2026
April 2026
M T W T F S S
 12345
6789101112
13141516171819
20212223242526
27282930  
Piezo1 Gain-of-Function Mutation Explains Thromboembolic Complications in Hereditary Xerocytosis – JTH
Journal of Thrombosis and Haemostasis (JTH)/LinkedIn
Feb 17, 2026, 15:27

Piezo1 Gain-of-Function Mutation Explains Thromboembolic Complications in Hereditary Xerocytosis – JTH

Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Christilla Bachelot-Loza et al, adding:

”Piezo1 gain of function induces a platelet preactivation state

Piezo1 gain-of-function mutations create a platelet preactivation state that enhances thrombosis risk, explaining thromboembolic complications in hereditary xerocytosis patients and revealing mechanosensitive ion channels as critical regulators of platelet hemostatic function.”

Title: Piezo1 gain of function induces a platelet preactivation state

Authors: Christilla Bachelot-Loza, Aurore Marchelli, Laurie Ruch, Divina El Hamaoui, Julien Demagny, Bruna Salau Grau, Clarisse Mouriaux, Wafa Amara, Anaïs Mehl, Emma Ziessel, Shaymaa Alhabib, My Ngoc Ha, Fatima Zemali, Sophie Gandrille, Véronique Picard, Pierre Mangin, Régis Bobe, Loïc Garçon, Catherine Léon, Pascale Gaussem

Read the Full Article on Journal of Thrombosis and Haemostasis.

Piezo1 Gain-of-Function Mutation Explains Thromboembolic Complications in Hereditary Xerocytosis - JTH

Stay updated on all scientific advances with Hemostasis Today.

bleeding disorders Health Hematology Hemostasis Hemostasis News Hemostasis Today Journal of Thrombosis and Haemostasis (JTH) Medicine thrombosis
NewsFeed