Wolfgang Miesbach: Synovitis and Haemophilia in Focus at GTH2026
Wolfgang Miesbach, Professor of Medicine at Frankfurt University Hospital, shared a post on LinkedIn:
”Joint Health in Focus: Synovitis and Haemophilia — Excellent presentation by Thomas Hilberg at GTH2026.
Synovitis remains poorly defined — especially the transition to ‘chronic’ — yet early and consistent treatment is essential to protect joint health.
Diagnosis: clinical exam plus imaging.
Ultrasound – practical for monitoring synovial hypertrophy.
MRI – superior for detecting post‑gadolinium enhancement, haemosiderin, and osteochondral damage, and shows where ultrasound reaches its limits.
Haemophilia treatment:
FVIII trough levels of ~8–12% are more effective than 3–5%, and in selected cases ≥30% for several months may be needed — yet many patients still show persistent hypertrophic synovium.
Treatment algorithms:
- Acute synovitis (<3 months): factor replacement/non‑factor therapy, arthrocentesis when indicated, short‑term anti‑inflammatory therapy, pain control, and stepwise physiotherapy with re‑evaluation after 4–6 weeks.
- Chronic synovitis (>3 months): re‑assess haemophilia treatment and diagnostics (incl. MRI), optimise anti‑inflammatory and pain control, intensify physiotherapy, and — if inadequate response — consider radiosynoviorthesis (RSO) and, ultimately, surgery.”
Stay updated with Hemostasis Today.
-
Oct 20, 2026, 04:13Ifeanyichukwu Ifechidere: DOACs Are Not the Answer to Every Anticoagulation Question
-
Oct 20, 2026, 04:04Sadia Kamal: Honored to Receive the Outstanding Abstract Award at the 20th Midwest Platelet Conference
-
Oct 20, 2026, 04:03Yu-Hsuan Chen: One Antibody, Two Diseases from FcRn Biology to Clinical Translation
-
Oct 20, 2026, 03:49Domenico Simone Castiello: Rethinking Prolonged DAPT in Multivessel PCI – Insights from the DAPT-MVD Trial
-
Oct 20, 2026, 03:37Rucha Patil: Scaling POC Diagnostics for Haemophilia A and VWD Across India
-
Oct 20, 2026, 03:31Zena Vexler: Targeting Neutrophil Elastase and NETosis to Mitigate Infection-Triggered Childhood Stroke
-
Oct 20, 2026, 03:24Chaza Alaji: Diagnosing Protein C and Protein S Deficiency
-
Oct 20, 2026, 03:24Mou Nandi: How Maternal Health During Pregnancy May Shape Infant Development
-
Oct 20, 2026, 03:13Sumyea Kabir: Pre-Analytical Quality in Phlebotomy – Preventing In Vitro Hemolysis