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Immunofluorescence Blood Smear Analysis Validated for Diagnosing Inherited Platelet Disorders – JTH
Apr 19, 2026, 12:51

Immunofluorescence Blood Smear Analysis Validated for Diagnosing Inherited Platelet Disorders – JTH

Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Carlo Zaninetti et al, published in JTH, adding:

”Interlaboratory Exercise on the Use of Immunofluorescence Microscopy on the Blood Smear for Recognizing Inherited Platelet Disorders: Communication from the ISTH SSC Subcommittee on Platelets in Health and Disease

This 7-laboratory validation study demonstrates that immunofluorescence-based platelet phenotyping on peripheral blood smears is a highly reproducible diagnostic tool for inherited platelet disorders, achieving consistent identification of conditions including MYH9-related disease, Bernard-Soulier syndrome, and Glanzmann thrombasthenia.”

Title: Interlaboratory exercise on the use of immunofluorescence microscopy on the blood smear for recognizing inherited platelet disorders: communication from the ISTH SSC Subcommittee on Platelets in Health and Disease

Authors: Carlo Zaninetti, Loredana Bury, Valeria Bozzi, Ana Zamora-Cánovas, Karina Althaus, Günalp Uzun, Simon Brown, Andrew Norman, Dorothée Faille, Alain Stepanian, Leo Kager, Sandra Ohlenforst, Carmen Freyer, Sina Semenowitsch, bruno giulio luigi bonisoli, Tamam Bakchoul, Alessandro Pecci, Paolo Gresele, Thomas Thiele, José Rivera, Andreas Greinacher

Immunofluorescence Blood Smear Analysis Validated for Diagnosing Inherited Platelet Disorders - JTH

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