Hemostasis Today

Tareq Abadl: Immune Thrombocytopenic Purpura vs Thrombotic Thrombocytopenic Purpura
May 31, 2026, 12:40

Tareq Abadl: Immune Thrombocytopenic Purpura vs Thrombotic Thrombocytopenic Purpura

Tareq Abadl, Medical Lab Specialist, shared a post on LinkedIn:

“Immune Thrombocytopenic Purpura vs Thrombotic Thrombocytopenic Purpura.

Same low platelets. Different danger.

Immune Thrombocytopenic Purpura (ITP)

  • Autoimmune platelet destruction
  • Bleeding disorder
  • PT/APTT usually normal
  • Large platelets on smear

Thrombotic Thrombocytopenic Purpura (TTP)

  • Platelet-rich microthrombi
  • Clotting and hemolysis disorder
  • Schistocytes on smear
  • Severe ADAMTS13 deficiency

Quick Smear Clue

  •  ITP – Large platelets
  •  TTP – Schistocytes

One causes bleeding.

One causes clotting and organ damage.”

Tareq Abadl: Immune Thrombocytopenic Purpura vs Thrombotic Thrombocytopenic Purpura

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