Intissar Haddiya: Can Low-Dose Rivaroxaban Improve Cardiovascular Outcomes in Patients with Advanced CKD?
Intissar Haddiya, Professor of Nephrology at Faculty of Medicine and Pharmacy of Oujda Mohammed First University, shared a post on LinkedIn about a recent article by Raja Ramachandran et al., published in JAMA, adding:
“Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney Disease (Track_Trial)
Can low-dose rivaroxaban improve cardiovascular outcomes in patients with advanced CKD?
In the TRACK randomized trial (1458 patients with CKD stage 4–5, including those on dialysis):
- No reduction in major cardiovascular events (HR 1.09; p=0.46)
- Higher rates of major bleeding (8.8% vs 6.0%)
- Low-dose rivaroxaban did not provide cardiovascular benefit and increased bleeding risk in this high-risk population.”
Title: Low-Dose Rivaroxaban and Cardiovascular Events in Advanced Kidney DiseaseThe TRACK Randomized Clinical Trial
Authors: Sunil V. Badve, Vlado Perkovic, Vivekanand Jha, Raja Ramachandran, Lily Mushahar, Jan Menne, An S. De Vriese, Patrick Rossignol, Adrien Flahault, Maha Al Ammari, Habib Skhiri, Michael Walsh, David Collister, Adrian Liew, Laurent Billot, Severine Bompoint, Anthony Devaux, Min Jun, Enmoore Lin, Aline Ramos da Cruz, Jeffrey T. Ha, John W. Eikelboom, Ahmed Shaman, Meg J. Jardine, Shilpanjali Jesudason, Muh Geot Wong, Craig S. Anderson, Amit X. Garg, Hiddo J. L. Heerspink, Helen Monaghan, Anushka Patel, Patrick B. Mark, David C. Wheeler, Jicheng Lv, Li Zuo, Helen Pilmore, Martin Gallagher
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 22, 2026, 16:13William Wallace: The Hidden Neurological Impact of Vitamin B12 Deficiency
-
Oct 22, 2026, 16:06Akram Farhadi: Anemia and Low Hemoglobin Associated With Higher Risk of Osteosarcopenia in Older Adults
-
Oct 22, 2026, 15:49Javed Iqbal: NUMC Pulmonary and Critical Care Team Showcases Research at CHEST 2026
-
Oct 22, 2026, 15:37Alina Mitina: Key Concerns Surrounding DVT and Pulmonary Embolism
-
Oct 22, 2026, 14:45Seyed Mehrab Safdari: Prenatal Diagnosis in Hemophilia – Two Decades of Progress and Remaining Challenges
-
Oct 22, 2026, 14:39Mahmoud Abdelnabi: Evaluating the Evidence on Elevated Lp(a) and VTE Before Clinical Translation
-
Oct 22, 2026, 14:34David McIntosh: Fundamental Flaws in National Blood Systems Are Root Causes of Failure
-
Oct 22, 2026, 14:32Aurelio Maggio: Bridging Scientific Progress and Equitable Access to SCD Care in Sub-Saharan Africa
-
Oct 22, 2026, 14:26Khaled Musallam: Longevity and Healthy Aging in Thalassemia