TNFα Role in Body’s Recovery from Anemia of Inflammation
Stefano Rivella, Leader of the RNA Gene Therapeutics group of The Penn Institute for RNA Innovation, shared a post on LinkedIn:
In a preclinical study, researchers at the Children’s Hospital of Philadelphia discovered that the cytokine tumor necrosis factor alpha (TNFα) plays a key role in aiding the body’s recovery from anemia of inflammation (AI), a blood disorder that can develop following chronic illness or infection.
The study was led by Dr. Amaliris Guerra, a former NIH T32 and Diversity Supplement Postdoctoral Trainee, CHOP Bridge to Faculty Fellow, and NIH Early-Stage Investigator Diversity Supplement Trainee, with co-authorship from Stefano Rivella, PhD, Kwame Ohene-Frempong Endowed Chair in Pediatric Hematology at CHOP.
Read Lauren Ingeno exploring the objectives.
Study: TNFα Plays Essential Role in Resolution of Anemia of Inflammation in Tnfαko Mice Treated with Heat-Killed Brucella Abortus
Authors: Vania Lo Presti, Ding-wen Chen, Ana Martins, Pankaj Sharma, Yelena Ginzburg, Carlo Castruccio Castracani, Carla Casu, Ritama Gupta, Raffaella Gozzelino, Edward Behrens, Laura F Bennett, Robert Paulson, Peter Kurre, Stefano Rivella, Amaliris Guerra
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