Ahmad Masri: The Amyloid Depleter Revolution in ATTR-CM
Ahmad Masri, Cardiomyopathy Section Head at Oregon Health & Science University, shared a post on LinkedIn about a recent article by Peter C. Kahr et al., published in Nature Medicine, adding:
“Longer term data from the cliramitug depleter program in ATTR-CM.
- The furthest along in development from this new class of drugs in ATTR.
- Cliramitug – phase III ongoing.
- Coramitug – enrolling now in phase III.
- AT02 – phase I-II.
2 new depleters in the preclinical settings – one from BridgeBio and one from Immutrin.”
Title: Cliramitug for depletion of cardiac amyloid transthyretin: long-term follow-up of the NI006-101 trial
Authors: Peter C. Kahr, Fabian aus dem Siepen, Olivier Lairez, Erwan Donal, Thibaud Damy, Arnt V. Kristen, Cristina C. Quarta, Michele F. Mercuri, Sarah Keppner-Witter, Eva Herrmann-Keiner, Mia Tichy, Aubin Michalon, Jan Grimm, Roger M. Nitsch, Christoph Hock, Pablo Garcia-Pavia, Peter van der Meer
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