Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure
Davide Capodanno, Full Professor of Cardiology at the University of Catania, shared a post on LinkedIn about recent articles, published in JAMA Cardiology, adding:
“No free lunch.
In our meta-analysis, now published in JAMA Cardiology, transcatheter left atrial appendage closure (LAAC) was associated with similar long-term risks of any stroke and major bleeding compared with oral anticoagulation in patients with atrial fibrillation, while increasing the risk of ischemic stroke and reducing the risk of nonprocedure-related major bleeding.”
Title: Catheter-Based Left Atrial Appendage Closure vs Oral Anticoagulation in Patients With Atrial FibrillationA Systematic Review and Meta-Analysis
Authors: Claudio Laudani, Kamil Bujak, Daniele Giacoppo, Simone Finocchiaro, Luigi Cutore, Maria Sara Mauro, Pietro Redigolo, Placido Maria Mazzone, Giacinto Di Leo, Francesco Nasisi, Marco Spagnolo, Antonio Greco, Davide Capodanno

Title: Left Atrial Appendage Occlusion vs Oral Anticoagulation—No Free Lunch
Authors: Jonathan P. Piccini

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