Davide Capodanno: The Trade-Offs of Left Atrial Appendage Closure
Davide Capodanno, Full Professor of Cardiology at the University of Catania, shared a post on LinkedIn about recent articles, published in JAMA Cardiology, adding:
“No free lunch.
In our meta-analysis, now published in JAMA Cardiology, transcatheter left atrial appendage closure (LAAC) was associated with similar long-term risks of any stroke and major bleeding compared with oral anticoagulation in patients with atrial fibrillation, while increasing the risk of ischemic stroke and reducing the risk of nonprocedure-related major bleeding.”
Title: Catheter-Based Left Atrial Appendage Closure vs Oral Anticoagulation in Patients With Atrial FibrillationA Systematic Review and Meta-Analysis
Authors: Claudio Laudani, Kamil Bujak, Daniele Giacoppo, Simone Finocchiaro, Luigi Cutore, Maria Sara Mauro, Pietro Redigolo, Placido Maria Mazzone, Giacinto Di Leo, Francesco Nasisi, Marco Spagnolo, Antonio Greco, Davide Capodanno

Title: Left Atrial Appendage Occlusion vs Oral Anticoagulation—No Free Lunch
Authors: Jonathan P. Piccini

Find more posts featuring Davide Capodanno on Hemostasis Today.
-
Oct 12, 2026, 11:51Daniel Sop: Sickle Cell Research Takes Center Stage at ASCAT 2026
-
Oct 12, 2026, 10:36PAI-1 Inhibition as a New Strategy for Enhancing Fibrinolysis and Clot Resolution
-
Oct 12, 2026, 07:39Emmanuel J Favaloro: 100 Years of von Willebrand Disease and the Importance of Local Diagnosis and Management
-
Oct 12, 2026, 07:39Post-Stroke Fatigue Trajectories – 38% Recovered at 12 Months, While 16% Developed New Fatigue – International Journal of Stroke
-
Oct 12, 2026, 07:28Beth Sara: IBMS Specialist Portfolio Achievement and a New Role in Transfusion Practice
-
Oct 12, 2026, 07:28Abdul Mannan: PCC vs. aPCC – The Small ‘a’ That Changes Emergency Management
-
Oct 12, 2026, 07:20Mokhtar Tazik: Improving Access to Plasma Derived Medicines Through Awareness, Interest and Accessibility
-
Oct 12, 2026, 07:08Larissa Chastain: Partnering to Transform Anticoagulation Management Through INR Self-Testing
-
Oct 12, 2026, 06:57Saiful Islam: Laboratory Spot Check – Microcytic Anemias and The Thalassemia Spectrum