Lukong Hubert Shalanyuy: New Research on Thromboplastin Reagents and PT/INR Reliability
Lukong Hubert Shalanyuy, Vice Chancellor University Institute of La Pointe – IUP, shared a post on LinkedIn about a recent article he and his colleagues co-authored, published in Open Access Library Journal, adding:
“I am honored to share another recent publication titled:
‘Comparative Evaluation of Bovine-Brain-Derived Thromboplastin versus Commercial Thromboplastin Reagents for Prothrombin Time and INR: A Pilot Experimental Study at National Polytechnic University Institute Medical Laboratory’, published in the Open Access Library Journal, Volume 13, Article e15743 (2026).
This pilot experimental study evaluated the analytical performance of locally prepared bovine-brain-derived thromboplastin against a commercial thromboplastin reagent for prothrombin time (PT) and international normalized ratio (INR) testing.
The findings demonstrated substantial variability and poor agreement between the two reagents, with the locally prepared bovine thromboplastin showing lower analytical reliability and a markedly different International Sensitivity Index.
The study has important implications for clinical laboratory medicine, hemostasis, anticoagulation monitoring and patient safety, particularly in resource-limited settings where locally prepared reagents may be used because of their affordability and accessibility.
The findings underscore the importance of reagent validation, calibration, standardization and quality assurance before laboratory methods are introduced into routine patient care.
I sincerely appreciate my co-authors and institutional collaborators whose contributions made this work possible.”
Title: Comparative Evaluation of Bovine-Brain-Derived Thromboplastin versus Commercial Thromboplastin Reagents for Prothrombin Time and INR: A Pilot Experimental Study at National Polytechnic University Institute Medical Laboratory
Authors: Lukong Hubert Shalanyuy, Fonyuy Husein Ali, Wam Elvis Chongsi, Romi Tungleh Toboh, Emmanuel Foncham
Stay updated with Hemostasis Today.
-
Aug 27, 2026, 13:52Terry Nguyen: VWD as the Most Common Bleeding Disorder
-
Aug 27, 2026, 13:49Sweta Kothari: Clinical Assessment of Thrombocytopenia Beyond Platelet Count
-
Aug 27, 2026, 13:43Claudio Laudani: Left Atrial Appendage Closure vs Anticoagulation in AF
-
Aug 27, 2026, 13:39Mili Jain: Key Causes and Diagnosis of Macrocytic Anemia
-
Aug 27, 2026, 13:28Strengthening Local Partnerships to Improve Haemophilia and Sickle Cell Care in the DRC – NNHF
-
Aug 27, 2026, 13:24Evolving Perspectives in Haemophilia B Management – EAHAD
-
Aug 27, 2026, 13:21Precious Cosmas: Sonographic Features and Practical Approach to Deep Vein Thrombosis Assessment
-
Aug 27, 2026, 13:20Mital Jhaveri: Anticoagulation in Advanced CKD – Why Individualized Decisions Matter
-
Aug 27, 2026, 13:15Praveen Kaudlay: Advancing Hemophilia Care in Davanagere