Mital Jhaveri: Anticoagulation in Advanced CKD – Why Individualized Decisions Matter
Mital Jhaveri, Clinical Anticoagulation, Heart Failure Pharmacist at NYC HHC Queens Hospital Center, shared a post on LinkedIn about a recent article by Kathrine Parker et al., published in BMC Nephrology Journals, adding:
“Anticoagulation in advanced kidney disease: when both clotting and bleeding risk are high, what is the right choice?
A newly published 2026 guideline highlights a challenge we face frequently in practice: patients with advanced CKD have increased risks of stroke, systemic embolism, and bleeding – yet they have historically been excluded from many major anticoagulation trials.
One particularly striking point: major DOAC trials largely excluded patients with CrCl less than 30 mL/min, leaving us with limited high-quality evidence precisely where thrombotic and bleeding risks are both high.
As a pharmacist working in anticoagulation, this reinforces that anticoagulation is never simply about choosing a drug and dose.
Renal function, bleeding risk, stroke risk, monitoring, and the individual patient all matter.
The best anticoagulation decision is an individualized one.”
Title: Anticoagulation for atrial fibrillation in adults with advanced kidney disease: UK kidney association clinical practice guideline
Authors: Kathrine Parker, Albert Power, Richard Buka, Mark Davies, Maria A. Gauci, Alan Hancock, John Hartemink, Anneka Mitchell, Honey Thomas, Jung Yin Tsang, Isaac Tseng, Andrew Turley, Gregory Y. H.
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 13, 2026, 02:01Nour Al-Mozain: Is It Really Anti-D? – Unraveling Auto-Anti-LW in the Transfusion Laboratory
-
Oct 13, 2026, 01:51Berenice Villegas: The Role of Morphologic Evaluation in Body Fluid Differential Analysis
-
Oct 13, 2026, 01:44Debadrita Ray: Evaluating vWF and VITRO Score for Detecting CSPH in cACLD Patients
-
Oct 13, 2026, 01:34Nagesh Ramesh: Donating Blood for International Plasma Awareness Week
-
Oct 12, 2026, 21:51Sam Botchey: Orthobiologics Are Advancing but the Evidence Must Keep Pace
-
Oct 12, 2026, 21:50Serum Vitamin D, Platelet Function, and Bleeding in Primary ITP – Platelets Journal
-
Oct 12, 2026, 21:30Nika Samadzadeh Tabrizi: Looking Forward to the PACeS Trial on Anticoagulation for POAF
-
Oct 12, 2026, 21:28Michael Megaly: Does Coronary Ectasia Affect Outcomes in Acute Coronary Syndromes?
-
Oct 12, 2026, 21:25Vitor Borin P. de Souza: Think Twice Before Anticoagulating an Isolated Subsegmental PE