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October, 2026
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Can Rivaroxaban and Edoxaban Be Used During Breastfeeding? – JTH
Aug 30, 2026, 10:32

Can Rivaroxaban and Edoxaban Be Used During Breastfeeding? – JTH

Journal of Thrombosis and Haemostasis (JTH) shared a post on LinkedIn about a recent article by Jignesh Patel, adding:

“Can edoxaban and rivaroxaban be prescribed for breastfeeding mothers? The New Horizons clinical trial

Postnatal VTE risk is high, yet many women find injectable low-molecular-weight heparin hard to tolerate.

This phase IV trial measured how two oral anticoagulants pass into breast milk.

Rivaroxaban transferred at low levels (milk:plasma ratio 0.2), while edoxaban mirrored maternal plasma (ratio 0.9).

Modeling predicted low infant exposure for both, with the evidence favoring rivaroxaban as breastfeeding-compatible.”

Title: Can edoxaban and rivaroxaban be prescribed for breastfeeding mothers? The New Horizons clinical trial

Authors: Jignesh Patel, Andrew J. Butler, Giula Mackina, Sinead Duffy, Juliet Scarlett, Jane Alcazar, Loreena Bacarro, Obianuju Nzelu, Hua Xu, Nina Ince, Lewis Couchman, Evangelia Vlachodimitropoulou, Roopen Arya

Can Rivaroxaban and Edoxaban Be Used During Breastfeeding? - JTH

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