Antonio Sorropago: Major Updates in Structural Heart Interventions
Antonio Sorropago, Interventional Cardiologist at Policlinico di Monza, shared a post on LinkedIn about a recent articles, adding:
“Updates in structural heart interventions just dropped at HOTLINE 7 ESCCongress
From optimizing post TAVI antithrombotic strategies to game changing T TEER Key takeaways and links to full papers
POPular ACE TAVI: Routine protamine administration after TAVI safely and significantly reduces the 30 day composite risk of mortality and bleeding compared to a selective approach, a benefit driven almost entirely by the prevention of minor Type 1 bleeds
TAVI PCI: For patients needing both TAVI and revascularization, performing TAVI first is noninferior to PCI first strategy at 1 year, validating a flexible valve first procedural sequence
TRIC I HF: In patients with severe tricuspid regurgitation and advanced heart failure, T TEER significantly improves 1 year QoL and clinical outcomes while slashing 3 year death or HF hospitalizations by 60 percent compared with OMT alone
ACASA TAVI: Twelve months of DOAC monotherapy after TAVI cuts subclinical leaflet thrombosis nearly in half compared with aspirin alone without compromising safety for bleeding, thromboembolic events or death
NOTION 4: A short 3 month DOAC regimen after TAVI only temporarily suppresses leaflet thickening on treatment showing no lasting prevention at 1 year and a higher composite risk of death, stroke or major bleeding compared with single antiplatelet therapy”
Title 1: Timing of PCI in Patients Undergoing Transcatheter Aortic-Valve Implantation
Authors: Barbara E. Stähli, Frank Ruschitzka, Dirk Westermann, Axel Linke, Norman Mangner, Nicolas M. Van Mieghem, Rahel Kesterke, Laura Oberholzer, Jürgen Rothe, Constantin von zur Mühlen, Tobias Zeus, Won-Keun Kim, Philipp Lauten, Nikos Werner, Christof Burgdorf, Hannes Alber, P. Christian Schulze, Michael Joner, Jonathan Michel, Alessandro Candreva, Philipp Jakob, Michael Würdinger, Julia Stehli, Alexander Gotschy, Christian Templin, Omer Dzemali, Luise Gaede, Steffen Massberg, Alexander Lauten, Frank van der Kley, Aydan Ewers, Thomas Nestelberger, Mohamed Abdel-Wahab, Giuseppe Musumeci, Sebastian Barth, Michael Hansen, Andreas Mügge, Moritz Seiffert, David M. Leistner, Thomas Cuisset, Steffen Schneider, Adnan Kastrati, Ian Ford, Markus A. Kasel
Read the Full Article on The New England Journal of Medicine
Title 2: Tricuspid Valve Intervention in Heart Failure
Authors: Jörg Hausleiter, Thomas J. Stocker, Tobias Geisler, Philipp Lurz, Wolfgang Rottbauer, Edith Lubos, Niklas Schofer, Christian Frerker, Johanne Frank, Holger Thiele, Rico Osteresch, Volker Rudolph, Alexander Lauten, Erion Xhepa, Jürgen Rothe, Tienush Rassaf, Stephan Baldus, Georg Nickenig, David M. Leistner, Eike Tigges, Victoria Kehl, Mirjam Kessler, Tobias Kister, Tobias Ruf, Muhammed Gerçek, Meinrad Gawaz, Derk Frank, Ingo Eitel, Ralph Stephan von Bardeleben, Daniel Kalbacher, Osama Soliman, Michael Näbauer, Steffen Massberg
Read the Full Article on The New England Journal of Medicine
Title 3: Anticoagulation Monotherapy vs Antiplatelet Monotherapy After Transcatheter Aortic Valve ImplantThe ACASA-TAVI Randomized Clinical Trial
Authors: Christopher S. Dodgson, Jon Herstad, Sophie F. Kløve, Malin Flygel, Mehdi Akhavi, Sverre Høie, Jan Otto Beitnes, Christian H. Eek, Kaspar Broch, Céline Cunen, Lars Gullestad, Lars Aaberge, Ketil Lunde, Bjørn Bendz, Øyvind H. Lie
Read the Full Article on JAMA
Title 4: Short-Term Anticoagulant Therapy and Subclinical Leaflet Thickening in Transcatheter Aortic Valves: The NOTION-4 Trial
Authors 4: Troels Højsgaard Jørgensen, Andreas Fuchs Larsen, Jesper Møller Jensen, Rebekka Vibjerg Jensen, Yannick Willemen, Aekapat Phoksiri, Arif Khokhar, Jani Thuraiaiyah, Kamilla Bech Pedersen, Gintautas Bieliauskas, Christian Juhl Terkelsen, Lars Søndergaard, Klaus Fuglsang Kofoed, Bjarne Linde Nørgaard, and Ole De Backer
Read the Full Article on JACC Journals.
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