Sanish Babu: The Hematocrit–Platelet Signal in Severe Dengue
Sanish Babu, MD Pathology shared a post on X:
”Dengue Management: Watch the Hematocrit (Hct), Not Just the Platelets
Thrombocytopenia is common, but plasma leakage is what turns dengue life-threatening.
Why serial Hematocrit is your most critical bedside marker:
The Capillary Leak Window:
- A rising Hct indicates hemoconcentration due to active plasma leakage.
- A greater than 20 percent increase defines severe plasma leakage.
The Red Flag Divergence:
- Rapidly falling platelets combined with a rising Hct suggests active capillary leakage and requires hospital admission and prompt initiation of intravenous crystalloids.
Fluid Titration Guide:
Rising Hct with unstable vital signs:
Increase intravenous fluid resuscitation.
Falling Hct with stable vital signs:
Gradually reduce intravenous fluids to prevent iatrogenic pulmonary edema.
Falling Hct with worsening shock:
Consider occult hemorrhage and transfuse blood rather than administering additional crystalloids.
Platelets show the diagnosis; hematocrit guides fluid resuscitation.”
Stay updated with Hemostasis Today.
-
Sep 8, 2026, 15:57Flora Peyvandi: Efficiency Meets Innovation in Hemophilia B Gene Therapy
-
Sep 8, 2026, 15:48Maxime Dely: Guillain-Barré Syndrome – What if the Key Lies in the Plasma?
-
Sep 8, 2026, 15:34Ron DePinho: A Negative Trial Highlights the Need for Precision in Cardiovascular Inflammation
-
Sep 8, 2026, 15:31Adil Yousaf: Thrombolysis Speed Matters, but Eligibility Comes First
-
Sep 8, 2026, 15:28Dhargam Aljebouri: First Molecularly Characterized Para-Bombay Phenotype in the Arab World
-
Sep 8, 2026, 15:27Mohd Ashhad: How Much Does Hemoglobin Increase After 1 Unit of PRBC?
-
Sep 8, 2026, 15:26Mary Kama: Climate-Informed Early Warning Systems for Sickle Cell Anaemia
-
Sep 8, 2026, 15:23Marissa Lechuga: Digital Transformation in Healthcare for People Living With SCD
-
Sep 8, 2026, 15:21Mohammed Javad Yousefi: Iron Deficiency and Anaemia Among Adolescent Girls in Iran