Chokri Ben Lamine: PNH beyond the Textbook Triad
Chokri Ben Lamine, Hematologist at King Faisal Specialist Hospital and Research Center, shared a post on X:
“PNH beyond the textbook triad
Key takeaways from Dr. Mohammed Almakadi, KFSH Almadinah, at SOHO KSA 2026.
Unexplained hemolysis, disproportionate anemia or atypical thrombosis in a myeloid neoplasm should prompt consideration of PNH testing.
Use high-sensitivity FLAER-based flow cytometry with lineage-specific clone quantification.
PNH can coexist with MPN or CML. Distinguish clinically significant disease from an incidental clone.
Integrate hemolysis, symptoms, thrombosis and clonal context. Clone detection alone does not justify complement inhibition.
Treat the patient, monitor the clone, and target complement when clinically indicated.”
Title 1: PNH clones prevalence study in ph-negative myeloproliferative neoplasms: a multicenter Italian study
Authors: Alessandra D’Addio, Michela Rondoni, Marzia Salvucci, Giovanni Marconi, Massimiliano Bonifacio, Ilaria Tanasi, Omar Perbellini, Giuseppe Carli, Patrizia Tosi, Simona Tomassetti, Giovanni Poletti, Evita Massari, Marco Rosetti, Elisabetta Fabbri, Chiara Zingaretti, Alessandro Lucchesi, Maria Teresa Bochicchio, Giorgia Simonetti, Mauro Krampera, Francesco Lanza
Read the Full Article on Annals of hematology
Title 2: When does a PNH clone have clinical significance?
Authors: Daria V Babushok
Read the Full Article on Hematology. American Society of Hematology. Education Program
Other posts featuring Chokri Ben Lamine on Hemostasis Today.
-
Oct 10, 2026, 17:58Archo Farzana Batool: Exploring Medical Writing Through an Article on Iron Deficiency Anemia
-
Oct 10, 2026, 17:53Assessing Frailty in Adults With Hemophilia – JTH
-
Oct 10, 2026, 17:52Fatma Sadeghi: Reducing Maternal Health Inequalities Through Nursing Advocacy
-
Oct 10, 2026, 17:50Grzegorz Hensler: How Apheresis Transformed Blood Cell Separation and Collection
-
Oct 10, 2026, 17:47Hemant K Sharma: Japan’s Universal Artificial Blood Research – A Potential Breakthrough in Transfusion Medicine
-
Oct 10, 2026, 17:40John Strouse: Learning About Bleeding Disorders and Sickle Cell Disease at FWGBD
-
Oct 10, 2026, 17:34Mae Caime: Speaking at the Annual Women’s Retreat for the Hemophilia Community in Florida
-
Oct 10, 2026, 17:29Ruah Alyamany: Thrombosis and Anticoagulation in Hematological Malignancies at SOHO KSA 2026
-
Oct 10, 2026, 17:28Juan José López Núñez: Bringing Patients and Families Together for World Thrombosis Day