John Abraham։ The Role of Diagnostic Splenectomy in Unexplained Splenomegaly
John Abraham, Assistant Professor at Christian Medical College and Hospital, shared a post on LinkedIn about a recent article by Nutan Joshi et al, published in the Indian Journal of Hematology and Blood Transfusion։
”Diagnostic Splenectomy in 2026 – Still Relevant?
A large single-center series (123 cases) from CMC Vellore revisits its role in unexplained splenomegaly.
Key Points:
- Diagnostic yield: 72%
- Lymphoma diagnosed: 58.5%
– 66% B-cell NHL (mainly SMZL, DLBCL)
– 23% T-cell
– Subtyping possible in ~88%
Predictors? None.
Age, B symptoms, LDH, splenic size, focal lesions — not reliably predictive.
Risk: 30-day mortality ~5% (sepsis most common)
Even in the PET-CT era, diagnostic splenectomy retains value — but strictly as a last-line diagnostic intervention.”
Title: Diagnostic Splenectomy: Clinical Profile, Role and Relevance in the Diagnosis of Lymphoma
Authors: Nutan Joshi, Sujith Karumathil, Sushil Selvarajan, Kavitha M. Lakshmi, S. Elanthenral, Santhosh Raj, Abi Manesh, Divya Susanna Ninan, Junita John, Myla Jacob, D. K. Titus, Uday Kulkarni, Biju George, Aby Abraham, Vikram Mathews, Anu Korula
Read the Full Article on Indian Journal of Hematology and Blood Transfusion.
Stay updated on all scientific advances with Hemostasis Today.
-
Oct 21, 2026, 03:36Steve Watson: Ligand Epitope Ratios Influence Antagonist Inhibition
-
Oct 21, 2026, 03:18Stephen D. Coombs: Superficial Venous Thrombosis in Athletes and Importance of Early Recognition and Referral
-
Oct 21, 2026, 02:52Aymar Akilimali: Bleeding During Anticoagulation as a Potential Signal of Occult Cancer
-
Oct 21, 2026, 00:58Anees Ur Rahman: Completing a Two-Week Clinical Rotation at Haemophilia Treatment Centre Rawalpindi
-
Oct 21, 2026, 00:56Caitlyn Mooney: Pulmonary Embolism in Athletes, Recognition and Return to Sport
-
Oct 21, 2026, 00:54Hani Karrar: Pleased to Share Our Review on Emicizumab in Hemophilia A Management
-
Oct 21, 2026, 00:53Akshay Sharma: HSCT Leads to Sustained Improvements in Sickle Cell Cardiomyopathy for Up to 3 Years
-
Oct 21, 2026, 00:51Prateek Meena: The F. A. T. R. N. Mnemonic for Recognizing TTP
-
Oct 20, 2026, 23:51Registration Is Open for WFH CCS 2027 – World Federation of Hemophilia