Neysa Rahardjo/LinkedIn
Oct 11, 2026, 15:07
Neysa Rahardjo: Platelet Estimation Pitfalls and Discrepancy Resolution
Neysa Rahardjo, Laboratory Manager at Rumah Sakit TNI AD Tk III 04.06.01 Wijayakusuma and RS Hermina Purwokerto, shared a post on LinkedIn:
“Platelet Estimation Pitfalls: Small Details, Significant Consequences
The Barbara Brown method is useful for platelet estimation, but several factors can compromise accuracy:
- Platelet clumping and satellitism.
- Giant or small platelets.
- Uneven platelet distribution.
- Poor smear quality or staining.
- An unvalidated multiplication factor.
How can we improve accuracy?
- Examine the entire smear and select a representative monolayer.
- Standardize field selection and counting procedures.
- Verify the multiplication factor locally.
- Correlate smear findings with analyzer results and clinical information.
Remember: Microscopic platelet estimation requires more than counting. Morphology, methodology, and clinical correlation matter.
How does your laboratory handle discrepancies between automated platelet counts and smear estimates?”
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