Vidyashri Hattigoudar: Essentials and Management of Hemophilia A
Vidyashri Hattigoudar, Clinical Manager at Shakti Hospital, shared a post on LinkedIn:
“Hemophilia A-Understanding the Bleeding Disorder
Hemophilia A is a rare inherited bleeding disorder caused by a deficiency or reduced activity of clotting factor VIII (FVIII).
Normally, clotting factors work together to stop bleeding. In Hemophilia A, insufficient FVIII makes it difficult for the blood to form a stable clot.
Common Features
- Prolonged bleeding after injuries, dental procedures, or surgery
- Easy bruising
- Recurrent bleeding into joints, especially knees, ankles, and elbows
- Bleeding into muscles and soft tissues
- In severe cases, bleeding may occur spontaneously
Why does it happen?
Hemophilia A is usually caused by a change (mutation) in the F8 gene, which provides instructions for making factor VIII. It is typically X-linked, meaning it mainly affects males, while females may be carriers.
Treatment and Management
Treatment aims to prevent and control bleeding. Options may include:
- Factor VIII replacement therapy
- Non-factor therapies such as emicizumab for appropriate patients
- Treatment plans tailored according to severity and individual needs
- Regular monitoring and comprehensive hemophilia care
Key message: Hemophilia A is a lifelong condition, but with early diagnosis, appropriate treatment, and proper care, people with Hemophilia A can live active and fulfilling lives.”
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