Ziad Omar/LinkedIn
May 26, 2026, 11:34
Ziad Omar: PTT and aPTT Testing – Reading the Intristic Pathway of Coagulation
Ziad Omar, Medical Laboratory Technician at Palestine Red Crescent Society, shared a post on LinkedIn:
“PTT / aPTT is one of the most important screening tests in coagulation, but its interpretation requires more than reading a number.
In this LabCore Education series, we explored the practical and scientific foundation of PTT / aPTT testing:
- Intrinsic and common pathway assessment
- Citrated plasma sample requirements
- 9:1 blood-to-citrate ratio
- Causes of prolonged PTT / aPTT
- Mixing study interpretation
- Practical mixing technique
- Inhibitors and lupus anticoagulant concepts
- Unfractionated heparin monitoring
- Pre-analytical errors
- PT vs PTT / aPTT comparison
The key takeaway:
A prolonged PTT / aPTT should always be interpreted in context — considering sample quality, medications, clinical history, and the need for further testing.
This series is designed for medical laboratory professionals, students, and healthcare workers who want a clear, practical approach to coagulation testing.”
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