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Laurent Pierre Burnier Shares the PINES Randomized Clinical Trial: Eltrombopag for Newly Diagnosed Pediatric ITP
Laurent Pierre Burnier/LinkedIn
Dec 26, 2025, 10:01

Laurent Pierre Burnier Shares the PINES Randomized Clinical Trial: Eltrombopag for Newly Diagnosed Pediatric ITP

Laurent Pierre Burnier, Biologist and FAMH candidate at Unilabs, shared a post on LinkedIn:

“In children newly diagnosed with immune thrombocytopenia (ITP) who need treatment but don’t have severe bleeding, eltrombopag leads to higher and more sustained platelet responses than standard first-line therapies such as steroids or IV immunoglobulin. It was well tolerated and may be considered an effective early treatment option, potentially reducing the need for repeated or rescue treatments.”

Title: Eltrombopag for Newly Diagnosed Pediatric Immune Thrombocytopenia Requiring Treatment – The PINES Randomized Clinical Trial

Authors: Kristin A. Shimano, Amanda B. Grimes, Shipra Kaicker, Sanjay J. Shah, Elizabeth Gunn, Rukhmi V. Bhat, Manpreet Kochhar, Jennifer A. Rothman, Melissa J. Rose, Michael Briones, Taizo A. Nakano, Jeffrey D. Lebensburger, Michele P. Lambert, Stephanie A. Fritch Lilla, Rohith Jesudas, Cathy A. Lee-Miller, Alexis A. Thompson, Stacey Rifkin-Zenenberg, Suvankar Majumdar, Shelley E. Crary, Kerry Hege, James B. Ford, Joshua J. Bies, John Fort, Tung T. Wynn, Loan Hsieh, Maritza E. Ruiz, Bogdan Dinu, Julia M. W. Wong, Pei-Chi Kao, Taylor O. Kim, Staci D. Arnold, Carolyn M. Bennett, Jenny M. Despotovic, Robert J. Klaassen, Ellis J. Neufeld, Cindy E. Neunert, Wendy B. London, Rachael F. Grace

Laurent Pierre Burnier Shares the PINES Randomized Clinical Trial: Eltrombopag for Newly Diagnosed Pediatric ITP

Read full paper here.

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Amanda B. Grimes Eltrombopag Health Hemostasis Hemostasis Today immune thrombocytopenia (ITP) Kristin A. Shimano Laurent Pierre Burnier Medicine Pediatric ITP Rachael F. Grace Shipra Kaicker the PINES thrombosis Wendy B. London
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