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Amy Goundry: Which Are The Next Major Advances in Blood and Plasma-Driven Immune Regulation?

Amy Goundry/LinkedIn

Feb 18, 2026, 12:34

Amy Goundry: Which Are The Next Major Advances in Blood and Plasma-Driven Immune Regulation?

Amy Goundry, Managing Editor at Sage, shared on LinkedIn:

”The blood–immune interface is a dynamic space where cellular and plasma components regulate immune responses across infection, inflammation, and systemic disease.

At Blood and Plasma we’re particularly interested in rigorous mechanistic research in this area, and we’ve just opened a Special Collection on it.

Which area of immune regulation by blood or plasma components will drive the next major advances?

Cellular crosstalk – How interactions among erythrocytes, platelets, leukocytes, and endothelium regulate immune activation and resolution
Plasma-mediated immune modulation – How complement, antibodies, cytokines, metabolites, and extracellular vesicles shape immune cell phenotype and function
Early biomarkers of dysregulation – Identifying markers that detect immune imbalance early and improve risk stratification and therapeutic targeting
Inflammation–coagulation links – How immune activation and coagulation pathways intersect in thrombosis, sepsis, and systemic inflammatory disease

Vote — and share what trends you’re seeing in your field!”

Amy Goundry: Which Are The Next Major Advances in Blood and Plasma-Driven Immune Regulation?