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TAILORED-CHIP Trial: Time-Dependent Antiplatelet Therapy in High-Risk PCI
Aug 21, 2025, 16:01

TAILORED-CHIP Trial: Time-Dependent Antiplatelet Therapy in High-Risk PCI

Ahmed Bennis, Professor of Cardiology, shared a post on X:

”Temporal modulation (early escalation and late de-escalation) of antiplatelet therapy in patients undergoing complex high-risk PCI: rationale and design of the TAILORED-CHIP trial

TAILORED-CHIP trial is an investigator-initiated, multicentre, prospective randomised trial to evaluate the efficacy and safety of a time-dependent tailored antiplatelet therapy with an early (<6 months post-PCI) escalation (low-dose ticagrelor at 60 mg twice daily plus aspirin) and a late (>6 months post-PCI) de-escalation (clopidogrel monotherapy) in patients undergoing complex high-risk PCI as compared with standard DAPT (clopidogrel plus aspirin for 12 months).”

Read the full article here.

Title: Temporal modulation (early escalation and late de-escalation) of antiplatelet therapy in patients undergoing complex high-risk PCI: rationale and design of the TAILORED-CHIP trial

Authors: Hanbit Park, Do-Yoon Kang, Jung-Min Ahn, Sung-Cheol Yun, Kyoung-Ha Park, Se-Hun Kang, Jon Suh, Jang-Whan Bae, Sangwoo Park, Jang Hyun Cho, Jung-Won Suh, Bong-Ki Lee, Seung-Woon Rha, Hoyoun Won, Jae-Sik Jang, Moo Hyun Kim, Cheol Hyun Lee, Young Keun Ahn, Jun-Hyok Oh, Jae-Seok Bae, Chul Soo Park, Jaewoong Choi, Jin-Bae Lee, Se-Whan Lee, Sung-Ho Hur, Osung Kwon, Seung-Jung Park, Duk-Woo Park; on behalf of the TAILORED-CHIP trial investigators

Antiplatelet

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