Aryabhatta Sadhu to Present Multivariable Predictors of Bleeding in Prophylactic Transfusion at ISBT 2025
Aryabhatta Sadhu, Senior Resident Doctor at AIIMS, shared on LinkedIn:
”From “more platelets” to “smarter transfusions.”
At International Society of Blood Transfusion (ISBT) 2025 (Perth), I’ll be presenting Poster BP061 — “Multivariable Predictors of Bleeding in Prophylactic Transfusion: Coagulopathy and Refractoriness Outweigh Platelet Concentrate Dosage.”
Our findings challenge the long-held “dose-response” paradigm in prophylactic transfusion.
Despite higher platelet increments with high-dose transfusions, bleeding outcomes remained unchanged.
Instead, coagulopathy (DIC) and refractoriness (spleen size, fever, chemo timing) emerged as the true drivers of bleeding risk.
This work pushes toward personalized, coagulation-integrated transfusion strategies—a necessary shift for safer, patient-centered care.
Poster: BP061, Exhibition hall, ground level, Perth convention and exhibition centre.
Venue: International Society of Blood Transfusion (ISBT) 2025, Perth, WA, Australia.
Colleagues and collaborators in transfusion medicine, hematology, and clinical research are welcome to connect for further discussions.”
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