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Aryabhatta Sadhu to Present Multivariable Predictors of Bleeding in Prophylactic Transfusion at ISBT 2025
Aryabhatta Sadhu/LinkedIn
Nov 8, 2025, 11:19

Aryabhatta Sadhu to Present Multivariable Predictors of Bleeding in Prophylactic Transfusion at ISBT 2025

Aryabhatta Sadhu, Senior Resident Doctor at AIIMS, shared on LinkedIn:

”From “more platelets” to “smarter transfusions.”

At International Society of Blood Transfusion (ISBT) 2025 (Perth), I’ll be presenting Poster BP061 — “Multivariable Predictors of Bleeding in Prophylactic Transfusion: Coagulopathy and Refractoriness Outweigh Platelet Concentrate Dosage.”

Our findings challenge the long-held “dose-response” paradigm in prophylactic transfusion.

Despite higher platelet increments with high-dose transfusions, bleeding outcomes remained unchanged.

Instead, coagulopathy (DIC) and refractoriness (spleen size, fever, chemo timing) emerged as the true drivers of bleeding risk.

This work pushes toward personalized, coagulation-integrated transfusion strategies—a necessary shift for safer, patient-centered care.

Poster: BP061, Exhibition hall, ground level, Perth convention and exhibition centre.
Venue: International Society of Blood Transfusion (ISBT) 2025, Perth, WA, Australia.

Colleagues and collaborators in transfusion medicine, hematology, and clinical research are welcome to connect for further discussions.”

Aryabhatta Sadhu to Present Multivariable Predictors of Bleeding in Prophylactic Transfusion at ISBT 2025

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Aryabhatta Sadhu bleeding disorders Bleeding Risk coagulation-integrated transfusion DIC Health Hematology Hemostasis Hemostasis Today ISBT 2025 Medicine Plasma Donation platelets smarter transfusions thrombosis Transfusion Medicine
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