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Bleeding Risk: Using DAPT Score to Minimize Complications While Maintaining Efficacy
Christopher Cannon/LinkedIn
Sep 23, 2025, 17:12

Bleeding Risk: Using DAPT Score to Minimize Complications While Maintaining Efficacy

Christopher Cannon, Editor in Chief, Harvard Health Publishing, shared a post on LinkedIn:

“A prospective randomized trial using the DAPT Risk score to tailor duration of DAPT – showing benefit in reducing bleeding and overall net benefit!!! I have been using the DAPT Risk score developed by Robert Yeh and Laura Mauri, but this is the first validation.

In the personalized DAPT duration arm, DAPT duration was 3 months for patients with low DAPT score and chronic coronary syndrome, 6 months for patients with low DAPT score and acute coronary syndrome, or 24 months for patients with high DAPT score (irrespective of the clinical presentation).
In the control arm, DAPT duration was 12 months”

Read full article here.

Title: Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation

Authors: Raffaele Piccolo, Paolo Calabrò, Greta Carrara, Fiorenzo Simonetti, Attilio Varricchio, Tiziana Attisano, Giovanni Napolitano, Ciro De Simone, Gerardo Carpinella, Eugenio Stabile, Plinio Cirillo, Luigi Di Serafino, Gianluca Caiazzo, Tullio Tesorio, Marco Boccalatte, Bernardino Tuccillo, Marisa Avvedimento, Attilio Leone, Gennaro Galasso, Arturo Cesaro, Rocco Perrotta, Tullio Niglio, Domenico Simone Castiello, Maddalena Immobile Molaro, Luca Bardi, Alessandra Spinelli, Stefano Cristiano, Michele Bellino, Sergio Leonardi, Simone Biscaglia, Francesco Costa, Salvatore Cassese, Eugene McFadden, Dik Heg, Giulio G. Stefanini, Anna Franzone, Davide Capodanno, Giovanni Esposito

Bleeding Risk: Using DAPT Score to Minimize Complications While Maintaining Efficacy

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Alessandra Spinelli Anna Franzone Arturo Cesaro Attilio Leone Attilio Varricchio Bernardino Tuccillo Bleeding Risk Cardiology Christopher Cannon Ciro De Simone Clinical Trial DAPT Score Davide Capodanno Dik Heg Domenico Simone Castiello Eugene McFadden Eugenio Stabile Fiorenzo Simonetti Francesco Costa Gennaro Galasso Gerardo Carpinella Gianluca Caiazzo Giovanni Esposito Giovanni Napolitano Giulio G. Stefanini Greta Carrara Health Hematology Hemostasis Hemostasis Today Luca Bardi Luigi Di Serafino Maddalena Immobile Molaro Marco Boccalatte Marisa Avvedimento Medicine Michele Bellino Paolo Calabrò Patient Care Personalized Medicine Plinio Cirillo Raffaele Piccolo Rocco Perrotta Salvatore Cassese Sergio Leonardi Simone Biscaglia Stefano Cristiano Tiziana Attisano Tullio Niglio Tullio Tesorio
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