Andrés Felipe Escobar González: Developing Anticoagulants That Prevent Thrombosis While Preserving Hemostasis
Andrés Felipe Escobar González, Pediatric Hematologist, Hemophilia Program at Medicarte, shared a post on LinkedIn about a recent article by Surasak Wichaiyo, published in JTH, adding:
“Received: 7 May 2026 – Revised: 9 July 2026 – Accepted: 3 August 2026
Educational Review
Pharmacology of anticoagulants: from heparin to novel target – specific agents
Surasak Wichaiyo
Anticoagulation therapy has undergone a remarkable evolution, from traditional agents such as heparin and vitamin K antagonists to direct oral anticoagulants and emerging therapies targeting specific coagulation factors.
In this review, ‘Pharmacology of Anticoagulants: From Heparin to Novel Target-Specific Agents,’ Surasak Wichaiyo explores the pharmacological mechanisms, clinical applications, and future perspectives of anticoagulant therapy, highlighting the growing interest in factor XI and XII inhibition.
One of the most exciting challenges in modern thrombosis research is developing anticoagulants that effectively prevent pathological thrombus formation while preserving physiological hemostasis and minimizing bleeding complications.
This evolving therapeutic landscape may open new opportunities for patients at high risk of both thrombosis and bleeding.”
Title: Pharmacology of anticoagulants: from heparin to novel target-specific agents
Authors: Surasak Wichaiyo
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