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Carlo Giulioni: Perioperative Management of Antithrombotics in Patients Undergoing Endoscopic Prostate Surgery
Carlo Giulioni/LinkedIn
Mar 5, 2026, 14:43

Carlo Giulioni: Perioperative Management of Antithrombotics in Patients Undergoing Endoscopic Prostate Surgery

Carlo Giulioni, Medical specialist at Villa Igea Nursing Home, shared on LinkedIn about a recent article he and his colleagues co-authored, adding:

”I’m thrilled to share the publication of meta-analysis on the perioperative management of antithrombotic therapy in patients undergoing endoscopic surgery for BPH, recently published in Prostate Cancer and Prostatic Diseases.

In this study, we analyzed 15 studies including 6,091 patients, comparing perioperative outcomes in patients undergoing endoscopic prostate surgery with ongoing antithrombotic therapy versus controls.

Main findings

  • Photoselective vaporization of the prostate (PVP) showed comparable perioperative outcomes, suggesting it may be a safe option when antithrombotic therapy cannot be interrupted.
  • TURP and endoscopic enucleation were associated with higher bleeding-related complications, particularly in patients on anticoagulant therapy.
  • Enucleation procedures also showed higher rates of bleeding requiring surgical hemostasis and acute urinary retention in anticoagulated patients.

Take-home message
Procedure selection is crucial in BPH patients on antithrombotic therapy, and PVP may represent the preferred surgical approach in patients requiring uninterrupted treatment, while decisions should always involve careful multidisciplinary risk assessment.

I am grateful to all the co-authors Daniele Castellani , Vineet Gauhar ,Luigi Schips , Angelo Cafarelli , Michele Marchioni , Luca Cindolo , Steffi Yuen , Carlotta Nedbal
who contributed to this work across multiple institutions and countries.”

Title: Perioperative outcomes of ongoing antithrombotic therapy during endoscopic surgery for benign prostatic hyperplasia: a systematic review and meta-analysis of observational studies

Authors: Carlo Giulioni, Angelo Cafarelli, Federico Falsetti, Luca Spinozzi, Angelo Cormio, Carlotta Nedbal, Valentina Maurizi, Steffi Kar Kei Yuen, Vineet Gauhar, Luca Cindolo, Michele Marchioni, Luigi Schips, Daniele Castellani

Read the Full Article on Prostate Cancer and Prostatic Diseases/Nature

Carlo Giulioni: Perioperative Management of Antithrombotics in Patients Undergoing Endoscopic Prostate Surgery

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Angelo Cafarelli Angelo Cormio Carlo Giulioni Carlotta Nedbal Daniele Castellani Federico Falsetti Health Hematology Hemostasis Hemostasis News Hemostasis Today Luca Cindolo Luca Spinozzi Luigi Schips Medicine Michele Marchioni Nature Photoselective vaporization Prostate Cancer and Prostatic Diseases PVP Steffi Kar Kei Yuen thrombosis TURP Valentina Maurizi Vineet Gauhar
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