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September, 2026
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Daniel I McIsaac: Less Blood Loss and No Excess VTE with Tranexamic Acid in High-Risk Surgery
Jun 11, 2026, 05:11

Daniel I McIsaac: Less Blood Loss and No Excess VTE with Tranexamic Acid in High-Risk Surgery

Daniel I McIsaac, Professor and Vice Chair of Research and Innovation in Department of Anesthesiology and Pain Medicine at University of Ottawa, shared on LinkedIn about a recent article he and his colleagues co-authored, published in NEJM, adding:

”For every 100 patients having surgeries with >=5% risk of transfusion that you treat with tranexamic acid you save 16 units of red blood cells AND YOU DON’T INCREASE VTE RISK.”

Title: Hospital Policy of Tranexamic Acid to Reduce Transfusion in Major Noncardiac Surgery

Authors: Brett L. Houston, Daniel I. McIsaac, Rodney H. Breau, Salmaan Kanji, Peter Greenstreet, Meghan Andrews, Sinziana Avramescu, Hema S. Bagry, Robert Balshaw, Jayesh Daya, Kaitlin Duncan, Christopher C. Harle, Eric Jacobsohn, Tina Kerelska, Marshall Pitz, Paul Komenda, Sarah McIsaac, Tim Ramsay, Tarit Saha, Alan Tinmouth, Angela Recio, Daniel Szoke, Marshall Tenenbein, Sarah Slagerman, Dayna Solvason, Robert Talarico, Dean A. Fergusson, Ryan Zarychanski

Daniel I McIsaac: Less Blood Loss and No Excess VTE with Tranexamic Acid in High-Risk Surgery

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