Dima Shulkin: Emerging Biomarkers for Early Prediction of Sepsis-Induced Shock
Dima Shulkin, Co-Founder and CTO at RobotDreams GmbH, shared a post on LinkedIn about a recent article by Jia Li et al, published in Frontiers in Pharmacology, adding:
“Could a blood test warn doctors hours before a sepsis patient takes a dangerous turn?
A 2026 review in Frontiers in Pharmacology by Li and colleagues explores that hope.
Sepsis is the body’s runaway reaction to infection.
When it goes far enough, blood pressure crashes and organs fail.
In some intensive care units, more than 4 in 10 of these patients die.
The authors look at tiny ‘warning signals’ in the blood that rise before the usual symptoms.
In one cited study of 142 patients, a signal called IL-6 correctly flagged the high-risk patients about 80 percent of the time.
Most signals still need testing before doctors can fully trust them.”
Title: Early biomarkers for predicting sepsis-induced shock: insights from inflammatory pathways and immune response
Authors: Jia Li, Qiufang Zhao, Haiyun Gao, Hongjun Wang, Cong Guo, Xiaoling Feng
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