Dima Shulkin: Assessing AI-Driven Blood Test Screening for Colorectal Cancer
Dima Shulkin, Co-Founder and CTO at RobotDreams GmbH, shared a post on LinkedIn about a recent article by Raeni Dwi Putri et al, published in Iranian Journal of Medical Sciences, adding:
“A blood-test cancer screen sounds like a breakthrough, until you see how many cancers it misses.
ColonFlag is a machine-learning tool that reads the ordinary blood test (the complete blood count) almost everyone has on file, looking for the faint anemia a hidden colon tumor can cause.
A 2024 review by Raeni Dwi Putri and colleagues in the Iranian Journal of Medical Sciences pulled together 10 studies, some covering millions of people.
The honest headline number: across most of the studies it caught only about 4 percent to 35 percent of cancers (two smaller prospective studies did better), far below a stool test or colonoscopy.
The authors say this plainly, and that candor is the point.”
Title: Efficacy of ColonFlag as a Complete Blood Count-Based Machine Learning Algorithm for Early Detection of Colorectal Cancer: A Systematic Review
Authors: Raeni Dwi Putri, Syifa Alfiah Sujana, Nadhira Nizza Hanifa, Tiffanie Almas Santoso, Murdani Abdullah

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