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Divyaswathi Citla Sridhar: How Bone Health Is Impacted in Bleeding Disorders
Divyaswathi Citla Sridhar/UAMS Health
May 25, 2026, 11:03

Divyaswathi Citla Sridhar: How Bone Health Is Impacted in Bleeding Disorders

Divyaswathi Citla Sridhar, Associate Professor of Pediatrics at UAMS – University of Arkansas for Medical Sciences, shared on LinkedIn about a recent article she and her colleagues co-authored, published in Blood Advances, adding:

”Exploring how bone health is impacted in bleeding disorders has been a central focus of my research for several years.

This question has guided the last 6 years of my research, and I’m excited to share our publication in Blood Advances: ‘Bone Mineral Density, Bone Remodeling Biomarkers, and Hemostatic Correlates in Hemophilia and von Willebrand Disease.’

Funded by the Arkansas Children’s Research Institute – Marion B. Lyon New Scientist Development Award, this prospective study explored the intersection of bone health and bleeding disorders, an area that remains underrecognized but critically important for long-term patient outcomes.

Our key findings:

  • Persons with Hemophilia and von Willebrand disease demonstrate measurable deficits in bone mineral density compared with healthy controls.
  • Higher thrombin generation was associated with higher bone mineral density in both groups

This work has been a true longitudinal effort and reflects the dedication of an incredible team of collaborators, mentors, and research participants.

Grateful to everyone who made this work possible: Simon Chung, Andrew Brown, Shelley E. Crary, Sanjay Ahuja, Steven Bruzek, Vera Ignjatović, Neil Goldenberg, Jin-Ran Chen.

I hope these findings contribute to a broader recognition that bone health should be an integral part of comprehensive care for people with bleeding disorders, and help advance earlier screening and targeted interventions.”

Title: Bone Mineral Density, Bone Remodeling Biomarkers, and Hemostatic Correlates in Hemophilia and von Willebrand Disease

Authors: Divyaswathi Citla-Sridhar, Simon Chung, Andrew W Brown, Shelley E Crary, Sanjay Ahuja, Steven Bruzek, Vera Ignjatovic, Neil A Goldenberg, Jin-Ran Chen

Divyaswathi Citla Sridhar: How Bone Health Is Impacted in Bleeding Disorders

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Andrew W Brown Arkansas Children's Research Institute bleeding disorders Blood Advances Bone health Divyaswathi Citla-Sridhar Health Hematology Hemophilia Hemostasis Hemostasis News Hemostasis Today Jin-Ran Chen Marion B. Lyon New Scientist Development Award Medicine Neil A. Goldenberg Sanjay Ahuja Shelley E Crary Simon Chung Steven Bruzek Vera Ignjatovic Von Willebrand Disease VWD
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